Challenges in elucidating the genetics of diabetic retinopathy

JZ Kuo, TY Wong, JI Rotter - JAMA ophthalmology, 2014 - jamanetwork.com
Importance In the past decade, significant progress in genomic medicine and technologic
developments has revolutionized our approach to common complex disorders in many …

The associations between VEGF gene polymorphisms and diabetic retinopathy susceptibility: a meta‐analysis of 11 case‐control studies

L Han, L Zhang, W Xing, R Zhuo, XL Lin… - Journal of diabetes …, 2014 - Wiley Online Library
Aims. Published data on the associations of VEGF polymorphisms with diabetic retinopathy
(DR) susceptibility are inconclusive. A systematic meta‐analysis was undertaken to clarify …

A unified framework for association analysis with multiple related phenotypes

M Stephens - PloS one, 2013 - journals.plos.org
We consider the problem of assessing associations between multiple related outcome
variables, and a single explanatory variable of interest. This problem arises in many settings …

Candidate gene studies of diabetic retinopathy in human

P Priščáková, G Minárik, V Repiská - Molecular biology reports, 2016 - Springer
Diabetic retinopathy (DR) is a multifactorial disease with complex pathophysiology. It is the
main cause of blindness among the people in productive age. The purpose of this literature …

The role of genetic polymorphisms in diabetic retinopathy: Narrative review

E Sienkiewicz-Szłapka, E Fiedorowicz… - International Journal of …, 2023 - mdpi.com
Diabetic retinopathy (DR) is renowned as a leading cause of visual loss in working-age
populations with its etiopathology influenced by the disturbance of biochemical metabolic …

Role of NF-κB activation and VEGF gene polymorphisms in VEGF up regulation in non-proliferative and proliferative diabetic retinopathy

S Choudhuri, IH Chowdhury, S Das, D Dutta… - Molecular and Cellular …, 2015 - Springer
The present study was aimed to investigate the relation between nuclear factor kappa beta
(NFκB) activation and downstream up-regulation of vascular endothelial growth factor …

Association between VEGF genetic variants and diabetic foot ulcer in Chinese Han population: a case–control study

X Li, Y Lu, P Wei - Medicine, 2018 - journals.lww.com
Association between VEGF genetic variants and diabetic foot... : Medicine Association between
VEGF genetic variants and diabetic foot ulcer in Chinese Han population: A case–control study …

[HTML][HTML] Candidate gene association study for diabetic retinopathy in Chinese patients with type 2 diabetes

X Yang, Y Deng, H Gu, X Ren, N Li, A Lim… - Molecular …, 2014 - ncbi.nlm.nih.gov
Purpose To investigate whether variants in a set of eight candidate genes are associated
with diabetic retinopathy (DR) in a cohort of Chinese patients with type 2 diabetes mellitus …

Association of VEGF gene polymorphisms with susceptibility to diabetic retinopathy: a systematic review and meta-analysis

Q Yang, Y Zhang, X Zhang, X Li… - Hormone and Metabolic …, 2020 - thieme-connect.com
The associations between vascular endothelial growth factor (VEGF) gene polymorphisms
and risk of type 2 diabetic retinopathy (DR)–proliferative diabetic retinopathy (PDR), and …

Association of vascular endothelial growth factor expression and polymorphisms with the risk of gestational diabetes mellitus

P Dong - Journal of clinical laboratory analysis, 2019 - Wiley Online Library
Objective To study the associations of vascular endothelial growth factor (VEGF) expression
and its gene polymorphisms with the risk of gestational diabetes mellitus (GDM). Methods A …