8-Hydroxyquinolines in medicinal chemistry: A structural perspective

V Oliveri, G Vecchio - European journal of medicinal chemistry, 2016 - Elsevier
Hydroxyquinolines are heterocyclic compounds characterized by a moderate metal-binding
affinity. The interest in 8-hydroxyquinolines has grown exponentially in the last two decades …

8-Hydroxyquinoline: A privileged structure with a broad-ranging pharmacological potential

H Xu, W Chen, P Zhan, X Liu - MedChemComm, 2015 - pubs.rsc.org
Privileged structures can bind to a diverse range of targets with high affinities, thus
benefiting the discovery of novel bioactive agents. 8-Hydroxyquinoline derivatives represent …

A superior corrosion protection of Mg alloy via smart nontoxic hybrid inhibitor-containing coatings

AS Gnedenkov, VS Filonina, SL Sinebryukhov… - Molecules, 2023 - mdpi.com
The increase of corrosion resistance of magnesium and its alloys by forming the smart self-
healing hybrid coatings was achieved in this work in two steps. In the first step, using the …

Visible light-driven α-sulfonylation of ketone-derived silyl enol ethers via an electron donor–acceptor complex

B Saxena, RI Patel, A Sharma - Green Chemistry, 2024 - pubs.rsc.org
The diverse utility of β-ketosulfones in pharmaceuticals and bioactive compounds has
generated considerable interest in their synthesis. However, existing synthetic approaches …

Photoinduced rearrangement of vinyl tosylates to β-ketosulfones

L Xie, X Zhen, S Huang, X Su, M Lin, Y Li - Green Chemistry, 2017 - pubs.rsc.org
We developed a photoinduced radical fragmentation and rearrangement of vinyl tosylates
that enables efficient formation of β-ketosulfones. This process is based on the photoinitiated …

Advances in schistosomiasis drug discovery based on natural products.

FL Mtemeli, J Ndlovu, G Mugumbate, T Makwikwi… - All Life, 2022 - Taylor & Francis
Schistosomiasis is a neglected tropical disease affecting over 250 million people worldwide.
The disease is the second most prevalent neglected tropical disease after malaria …

Advanced technologies for screening and identifying covalent inhibitors

Y Guo, A Tong, Y Wang - TrAC Trends in Analytical Chemistry, 2024 - Elsevier
Covalent inhibitors, forming reversible or irreversible covalent bonds with nucleophilic
groups in target protein active sites, effectively inhibit protein function for therapeutic …

Current drug targets for helminthic diseases

AK Rana, S Misra-Bhattacharya - Parasitology Research, 2013 - Springer
More than 2 billion people are infected with helminth parasites across the globe. The
burgeoning drug resistance against current anthelmintics in parasitic worms of humans and …

[HTML][HTML] Microwave-assisted hydrothermal fabrication of hierarchical-stacked mesoporous decavanadate-intercalated ZnAl nanolayered double hydroxide to …

AS Darwish, SS Mahmoud, FEA Bayaumy - Heliyon, 2023 - cell.com
Hierarchically stacked mesoporous zinc-aluminium nanolayered-double-hydroxide
intercalated with decavanadate (ZnAl-LDH-V 10 O 28) is constructed using anion-exchange …

Green synthesis and immobilization of TiO2 NPs using ILs-based on imidazole and investigation of its catalytic activity for the efficient synthesis of pyrimido [4, 5-d] …

R Bakhshali-Dehkordi, MA Ghasemzadeh… - Journal of Molecular …, 2020 - Elsevier
Abstract In this study pyrimido [4, 5-d] pyrimidine derivatives have been synthesized via a
suitable and efficient procedure using one-pot multi-component reactions of …