Lipid and carbohydrate metabolism are highly conserved processes that affect nearly all
aspects of organismal biology. Caenorhabditis elegans eat bacteria, which consist of lipids …

Caenorhabditis elegans is an exceptionally valuable model for aging research because of
many advantages, including its genetic tractability, short lifespan, and clear age‐dependent …

Online application for survival analysis (OASIS) has served as a popular and convenient
platform for the statistical analysis of various survival data, particularly in the field of aging …

Emerging evidence indicates that the accretion of senescent cells is linked to metabolic
disorders. However, the underlying mechanisms and metabolic consequences of cellular …

Chromatin and metabolic states both influence lifespan, but how they interact in lifespan
regulation is largely unknown. The COMPASS chromatin complex, which trimethylates …

Ageing is a complex trait controlled by genes and the environment. The highly conserved
mechanistic target of rapamycin signalling pathway (mTOR) is a major regulator of lifespan …

This chapter focuses on the introduction of molecular signaling pathways involved in
regulating the toxicity of environmental toxicants or stresses in Caenorhabditis elegans …

Caenorhabditis elegans has been used as a major model organism to identify genetic
factors that regulate organismal aging and longevity. Insulin/insulin-like growth factor 1 (IGF …

Caenorhabditis elegans (C. elegans) is a free-living nematode that has been extensively
utilized as an animal model for research involving aging and neurodegenerative diseases …

Ferroptosis is an iron-dependent form of regulated cell death associated with uncontrolled
membrane lipid peroxidation and destruction. Previously, we showed that dietary dihomo …