Nanoparticulate drugs and vaccines: breakthroughs and bottlenecks of repurposing in breast cancer

P Kumbhar, K Kole, V Khadake, P Marale… - Journal of Controlled …, 2022 - Elsevier
Breast cancer (BC) is a highly diagnosed and topmost cause of death in females worldwide.
Drug repurposing (DR) has shown great potential against BC by overcoming major …

Dual targeting of mTOR/IL-17A and autophagy by fisetin alleviates psoriasis-like skin inflammation

T Roy, S Banang-Mbeumi, ST Boateng… - Frontiers in …, 2023 - frontiersin.org
Psoriasis is a chronic autoimmune inflammatory skin disorder characterized by epidermal
hyperplasia and aberrant immune response. In addition to aberrant cytokine production …

The future of cancer vaccines against colorectal cancer

W Jia, X Shen, Z Guo, X Cheng… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Colorectal cancer (CRC) is the second most lethal malignancy worldwide.
Immune checkpoint inhibitors (ICIs) benefit only 15% of patients with mismatch repair …

[PDF][PDF] Cancer vaccines: anti-tumoral t cell therapy on demand

M Fusciello - 2023 - helda.helsinki.fi
In the 1890s, William B. Coley (figure below), an American bone surgeon, injects in patients
with solid tumors post-surgery a streptococcal organism [1]. In his opinion, this activated the …

[PDF][PDF] Intratumoral induktion af type I-interferonrespons i solide tumorer

L Löffler, I Gögenur, S Brix, M Gögenur - Ugeskr Læger, 2023 - content.ugeskriftet.dk
Cancerregisteret viser en stigning i incidens af solide tumorer i Danmark på 21% for mænd
og 14% for kvinder i perioden 2009-2019. I 2019 blev 45.453 patienter diagnosticeret med …