Colon microbiota fermentation of dietary prebiotics towards short-chain fatty acids and their roles as anti-inflammatory and antitumour agents: A review

J Fernández, S Redondo-Blanco… - Journal of Functional …, 2016 - Elsevier
Some plant polysaccharides cannot be digested by humans, arriving intact to the colon,
where they are fermented by a distinct group of anaerobic beneficial bacterial species …

Intestinal alkaline phosphatase: novel functions and protective effects

JP Lallès - Nutrition reviews, 2014 - academic.oup.com
Important protective roles of intestinal alkaline phosphatase (IAP)–including regulation of
intestinal surface pH, absorption of lipids, detoxification of free nucleotides and bacterial …

Prebiotics in chronic intestinal inflammation

MAC Looijer–Van Langen… - Inflammatory bowel …, 2009 - academic.oup.com
Prebiotics are nondigestible fermentable fibers that are reported to have health benefits for
the host. Older as well as more recent studies show beneficial effects in experimental colitis …

[HTML][HTML] An α-linolenic acid-rich formula reduces oxidative stress and inflammation by regulating NF-κB in rats with TNBS-induced colitis

A Hassan, A Ibrahim, K Mbodji, M Coëffier… - The Journal of …, 2010 - Elsevier
We have previously shown that α-linolenic acid (ALA), a (n-3) PUFA exerts in vitro
antiinflammatory effects in the intestine. In this study, we aimed to evaluate its effect on …

Targeting gut barrier dysfunction with phytotherapies: Effective strategy against chronic diseases

P Dey - Pharmacological research, 2020 - Elsevier
The intestinal epithelial layer serves as a physical and functional barrier between the
microbe-rich lumen and immunologically active submucosa; it prevents systemic …

Prebiotic oligosaccharides directly modulate proinflammatory cytokine production in monocytes via activation of TLR 4

F Capitán‐Cañadas… - Molecular nutrition & …, 2014 - Wiley Online Library
Scope Prebiotic oligosaccharides are currently used in a variety of clinical settings for their
effects on intestinal microbiota. Here, we have examined the direct, microbiota independent …

The effects of Δ9‐tetrahydrocannabinol and cannabidiol alone and in combination on damage, inflammation and in vitro motility disturbances in rat colitis

JM Jamontt, A Molleman, RG Pertwee… - British journal of …, 2010 - Wiley Online Library
Background and purpose: Cannabis is taken as self‐medication by patients with
inflammatory bowel disease for symptomatic relief. Cannabinoid receptor agonists decrease …

Nondigestible oligosaccharides exert nonprebiotic effects on intestinal epithelial cells enhancing the immune response via activation of TLR 4‐NF κ B

M Ortega‐González, B Ocón… - Molecular nutrition & …, 2014 - Wiley Online Library
Scope Prebiotic effects of non absorbable glucids depend mainly on digestion by the colonic
microbiota. Our aim was to assess nonprebiotic, direct effects of 4 prebiotics, namely …

Protective effects of β-glucan isolated from highland barley on ethanol-induced gastric damage in rats and its benefits to mice gut conditions

H Chen, Q Nie, M Xie, H Yao, K Zhang, J Yin… - Food research …, 2019 - Elsevier
Gastrointestinal tract disease is a global health problem which affects a major part of the
world population. In this study, the gastroprotective effects of β-glucan isolated from highland …

Pathobiology and potential therapeutic value of intestinal short-chain fatty acids in gut inflammation and obesity

J Soldavini, JD Kaunitz - Digestive diseases and sciences, 2013 - Springer
Background The lumen of the gastrointestinal tract contains many substances produced
from the breakdown of foodstuffs, from salivary, esophageal, intestinal, hepatic, and …