Platelets play a variety of roles in vascular biology and are best recognized as primary
hemostasis and thrombosis mediators. Platelets have a large number of receptors and …

Epithelial tissues protecting organs from the environment are the first-line of defense against
pathogens. Therefore, efficient repair mechanisms after injury are crucial to maintain …

Angiogenesis is a hallmark of malignant neoplasias, as the formation of new blood vessels
is required for tumors to acquire oxygen and nutrients essential for their continued growth …

EVs are membranous subcellular structures originating from various cells, including
platelets which consist of biomolecules that can modify the target cell's pathophysiological …

Background Pustular skin disorders are a category of difficult-to-treat and potentially life-
threatening conditions that involve the appearance of neutrophil-rich pustules. The …

Pseudomonas aeruginosa and Staphylococcus aureus are the two dominant Gram-negative
and-positive species, respectively, isolated from patients with contact lens-related bacterial …

Epidemic keratoconjunctivitis (EKC), caused by human adenovirus (HAdV), is one of the
most common ocular infections and results in corneal inflammation and subepithelial …

Bacterial keratitis is a disease of the cornea characterized by pain, redness, inflammation,
and opacity. Common causes of this disease are Pseudomonas aeruginosa and …

Some tissues of the eye are susceptible to damage due to their exposure to the outside
environment and inability to regenerate. Immune privilege, although beneficial to the eye in …

Abstract The Gram-negative bacteria Brucella abortus is a major cause of brucellosis in
animals and humans. The host innate immune response to B. abortus is mainly associated …