Two New Rapid SNP-Typing Methods for Classifying Mycobacterium tuberculosis Complex into the Main Phylogenetic Lineages

D Stucki, B Malla, S Hostettler, T Huna, J Feldmann… - PloS one, 2012 - journals.plos.org
There is increasing evidence that strain variation in Mycobacterium tuberculosis complex
(MTBC) might influence the outcome of tuberculosis infection and disease. To assess …

Digital PCR to Detect and Quantify Heteroresistance in Drug Resistant Mycobacterium tuberculosis

S Pholwat, S Stroup, S Foongladda, E Houpt - PloS one, 2013 - journals.plos.org
Drug resistance in Mycobacterium tuberculosis presents an enormous public health threat. It
is typically defined as> 1% of drug resistant colonies using the agar proportion method …

Tuberculosis drug resistance testing by molecular methods: opportunities and challenges in resource limited settings

G Abebe, F Paasch, L Apers, L Rigouts… - Journal of …, 2011 - Elsevier
One of the greatest threats to global tuberculosis (TB) control is the growing prevalence of
drug-resistant bacilli. Correctly diagnosing drug-resistant TB patients is more problematic in …

Rapid identification of Brucella isolates to the species level by real time PCR based single nucleotide polymorphism (SNP) analysis

KK Gopaul, MS Koylass, CJ Smith, AM Whatmore - BMC microbiology, 2008 - Springer
Background Brucellosis, caused by members of the genus Brucella, remains one of the
world's major zoonotic diseases. Six species have classically been recognised within the …

Rapid detection of ERG11 gene mutations in clinical Candida albicans isolates with reduced susceptibility to fluconazole by rolling circle amplification and DNA …

H Wang, F Kong, TC Sorrell, B Wang, P McNicholas… - BMC microbiology, 2009 - Springer
Background Amino acid substitutions in the target enzyme Erg11p of azole antifungals
contribute to clinically-relevant azole resistance in Candida albicans. A simple molecular …

[HTML][HTML] Establishment of an A/T-Rich Specifically MGB Probe digital droplet PCR Assays Based on SNP for Brucella wild strains and vaccine strains

W Li, S Zhang, S Dang, L Gao, G Li, D Cheng… - … and Infectious Disease, 2024 - Elsevier
In recent years, immunization with the S2 live-attenuated vaccine has been recognized as
the most economical and effective strategy for preventing brucellosis in Inner Mongolia …

Multiplex Assay Based on Single-Nucleotide Polymorphisms for Rapid Identification of Brucella Isolates at the Species Level

JC Scott, MS Koylass, MR Stubberfield… - Applied and …, 2007 - Am Soc Microbiol
The genus Brucella includes a number of species that are major animal pathogens
worldwide and significant causes of zoonotic infections of humans. Traditional methods of …

Allele-specific isothermal amplification method using unmodified self-stabilizing competitive primers

K Malpartida-Cardenas, J Rodriguez-Manzano… - Analytical …, 2018 - ACS Publications
Rapid and specific detection of single nucleotide polymorphisms (SNPs) related to drug
resistance in infectious diseases is crucial for accurate prognostics, therapeutics and …

Dissemination of novel antimicrobial resistance mechanisms through the insertion sequence mediated spread of metabolic genes

L Furi, R Haigh, ZJH Al Jabri, I Morrissey… - Frontiers in …, 2016 - frontiersin.org
The widely used biocide triclosan selectively targets FabI, the NADH-dependent trans-2-
enoyl-acyl carrier protein (ACP) reductase, which is also an important target for the …

Fluoroquinolone resistance detection in Mycobacterium tuberculosis with locked nucleic acid probe real-time PCR

HR Van Doorn, DD An, MD De Jong… - … of Tuberculosis and …, 2008 - ingentaconnect.com
SETTING: Pham Ngoc Thach Hospital for Tuberculosis and Lung Diseases, Ho Chi Minh
City, Vietnam. OBJECTIVE: Fluoroquinolones (FQs) are increasingly used in the treatment of …