New perspectives on the origins and heterogeneity of mast cells
Mast cells are immune cells of the haematopoietic lineage that are now thought to have
multifaceted functions during homeostasis and in various disease states. Furthermore, while …
multifaceted functions during homeostasis and in various disease states. Furthermore, while …
Mast cells in inflammation and disease: recent progress and ongoing concerns
Mast cells have existed long before the development of adaptive immunity, although they
have been given different names. Thus, in the marine urochordate Styela plicata, they have …
have been given different names. Thus, in the marine urochordate Styela plicata, they have …
Targeting interleukin-33 and thymic stromal lymphopoietin pathways for novel pulmonary therapeutics in asthma and COPD
AA Calderon, C Dimond, DF Choy… - European …, 2023 - Eur Respiratory Soc
Interleukin-33 (IL-33) and thymic stromal lymphopoietin (TSLP) are alarmins that are
released upon airway epithelial injury from insults such as viruses and cigarette smoke, and …
released upon airway epithelial injury from insults such as viruses and cigarette smoke, and …
[HTML][HTML] Neutrophil trapping and nexocytosis, mast cell-mediated processes for inflammatory signal relay
M Mihlan, S Wissmann, A Gavrilov, L Kaltenbach… - Cell, 2024 - cell.com
Neutrophils are sentinel immune cells with essential roles for antimicrobial defense. Most of
our knowledge on neutrophil tissue navigation derived from wounding and infection models …
our knowledge on neutrophil tissue navigation derived from wounding and infection models …
Mast cells in the skin: defenders of integrity or offenders in inflammation?
Mast cells (MCs) are best-known as key effector cells of immediate-type allergic reactions
that may even culminate in life-threatening anaphylactic shock syndromes. However …
that may even culminate in life-threatening anaphylactic shock syndromes. However …
Mast cell-mediated orchestration of the immune responses in human allergic asthma: current insights
D Elieh Ali Komi, L Bjermer - Clinical reviews in allergy & immunology, 2019 - Springer
Improving the lung function after experimental allergen challenge by blocking of mast cell
(MC) mediators and the capability of MC mediators (including histamine, prostaglandin (PG) …
(MC) mediators and the capability of MC mediators (including histamine, prostaglandin (PG) …
Association of differential mast cell activation with granulocytic inflammation in severe asthma
Rationale: Mast cells (MCs) play a role in inflammation and both innate and adaptive
immunity, but their involvement in severe asthma (SA) remains undefined. Objectives: We …
immunity, but their involvement in severe asthma (SA) remains undefined. Objectives: We …
Interferon inducible X-linked gene CXorf21 may contribute to sexual dimorphism in Systemic Lupus Erythematosus
CA Odhams, AL Roberts, SK Vester, CST Duarte… - Nature …, 2019 - nature.com
Systemic lupus erythematosus (SLE) is an autoimmune disease, characterised by increased
expression of type I interferon (IFN)-regulated genes and a striking sex imbalance towards …
expression of type I interferon (IFN)-regulated genes and a striking sex imbalance towards …
Understanding mast cell heterogeneity at single cell resolution
Mast cells (MC) s are evolutionarily conserved, tissue-resident immune cells with diverse
roles in allergy, cancer, and protection from infection by helminths and microorganisms. The …
roles in allergy, cancer, and protection from infection by helminths and microorganisms. The …
[HTML][HTML] Effects of G-Rh2 on mast cell-mediated anaphylaxis via AKT-Nrf2/NF-κB and MAPK-Nrf2/NF-κB pathways
C Xu, L Li, C Wang, J Jiang, L Li, L Zhu, S Jin… - Journal of Ginseng …, 2022 - Elsevier
Background The effect of ginsenoside Rh2 (G-Rh2) on mast cell-mediated anaphylaxis
remains unclear. Herein, we investigated the effects of G-Rh2 on OVA-induced asthmatic …
remains unclear. Herein, we investigated the effects of G-Rh2 on OVA-induced asthmatic …