Extracellular matrix proteins are regulated by metzincin proteases, like the disintegrin
metalloproteinases with thrombospondin motifs (ADAMTS) family members. This review …

Thoracic aortic aneurysm and dissection (TAAD) are complex disease states with high
morbidity and mortality that pose significant challenges to early diagnosis. Patients with an …

Pathological cardiac remodeling as an aftermath of a severe cardiac injury can lead to
ventricular dysfunction and subsequent heart failure. Adamts4, a metalloproteinase, and …

Background As an inflammation-related cytokine, interleukin (IL)-5 has been reported to be
involved in the development of cardiovascular diseases, such as chronic heart failure and …

New Findings What is the central question of this study? Thoracic aortic aneurysm and
dissection (TAAD) is characterized by extracellular matrix remodelling and an inflammatory …

Some biomarkers of acute aortic dissection (AAD) can be used for the potential
supplementary diagnosis of AAD, such as C-reactive protein (CRP), smooth muscle myosin …

Despite significant advances in imaging modalities for diagnosing coronary artery disease
(CAD), there remains a need for novel diagnostic approaches with high predictive values …

Acute respiratory distress syndrome (ARDS) has no specific and effective treatment, and
there is an urgent need to understand its pathogenesis. Therefore, based on the hypothesis …

An aortic aneurysm is a localized enlargement that exceeds the normal diameter of the
vessel by 50%, posing a risk due to the likelihood of rupture. The cause of aortic aneurysm …

Aortic dissection (AD) is a potentially fatal cardiovascular issue that needs to be diagnosed
and treated very away. Although early detection is essential for bettering patient outcomes …