VEGF-dependent tumor angiogenesis requires inverse and reciprocal regulation of VEGFR1 and VEGFR2

Z Zhang, KG Neiva, MW Lingen, LM Ellis… - Cell Death & …, 2010 - nature.com
Vascular endothelial growth factor (VEGF) signaling is critical for tumor angiogenesis.
However, therapies based on inhibition of VEGF receptors (VEGFRs) have shown modest …

Bridging the Gap: Advanced Biosensor Technologies for Early-Stage Oral Cancer Diagnosis Based on Biomarker Detection

ZB AKSOY, DB IL, D Celik, DN SENGUN… - TrAC Trends in …, 2024 - Elsevier
This paper examines the recent strides in biosensor technologies aimed at revolutionizing
the early detection of oral cancer. Early diagnosis is pivotal in enhancing treatment efficacy …

Objectives and applications of phenotyping network set‐up for livestock

JF HOCQUETTE, C Capel, V David… - Animal Science …, 2012 - Wiley Online Library
Providing phenotypic information, which is accurate, reliable, repeatable and comparable
across countries or laboratories, is critical to gain a better understanding of the relationship …

Hypoxia-induced energy stress inhibits the mTOR pathway by activating an AMPK/REDD1 signaling axis in head and neck squamous cell carcinoma

A Schneider, RH Younis, JS Gutkind - Neoplasia, 2008 - Elsevier
The mammalian target of rapamycin (mTOR) signaling network is frequently hyperactivated
in patients with head and neck squamous cell carcinoma (HNSCC). Recent studies suggest …

Surgical management of oropharyngeal squamous cell carcinoma: survival and functional outcomes

B Kumar, MJ Cipolla, MO Old, NV Brown… - Head & …, 2016 - Wiley Online Library
Background The purpose of this study was to further define the impact of primary surgery in
the management of oropharyngeal squamous cell carcinoma (SCC). Methods Two hundred …

Prediction and analysis of key genes in glioblastoma based on bioinformatics

H Long, C Liang, X Zhang, L Fang… - BioMed research …, 2017 - Wiley Online Library
Understanding the mechanisms of glioblastoma at the molecular and structural level is not
only interesting for basic science but also valuable for biotechnological application, such as …

Multiple genetic copy number alterations in oral squamous cell carcinoma: study of MYC, TP53, CCDN1, EGFR and ERBB2 status in primary and metastatic …

G Martín‐Ezquerra, R Salgado, A Toll… - British Journal of …, 2010 - academic.oup.com
Background Oncogenesis in the oral cavity is believed to result from genetic alterations that
cause a stepwise transformation of the mucosa to invasive carcinoma. In oral squamous cell …

[HTML][HTML] Tissue microarray is a reliable method for immunohistochemical analysis of pleomorphic adenoma

FP Fonseca, BAB de Andrade, ALCA Rangel… - Oral surgery, oral …, 2014 - Elsevier
Objective To determine the most adequate number and size of tissue microarray (TMA)
cores for pleomorphic adenoma immunohistochemical studies. Study design Eighty-two …

EGFR and Ki‐67 expression in oral squamous cell carcinoma using tissue microarray technology

LS Monteiro, M Diniz‐Freitas… - Journal of oral …, 2010 - Wiley Online Library
J Oral Pathol Med (2010) 39: 571–578 Objective: Our aim was to validate the use of tissue
microarrays (TMA) in oral squamous cell carcinomas (OSCC) to analyse epidermal growth …

Cytoplasmic accumulation of activated leukocyte cell adhesion molecule is a predictor of disease progression and reduced survival in oral cancer patients

M Sawhney, A Matta, MA Macha, J Kaur… - … journal of cancer, 2009 - Wiley Online Library
Activated leukocyte cell adhesion molecule (ALCAM) has been proposed to function as a
cell surface sensor for cell density, controlling the transition between local cell proliferation …