Dysregulation of the bone marrow niche resulting from the direct and indirect effects of HIV
infection contributes to haematological abnormalities observed in HIV patients. The bone …

The evolution of structural proteins is generally constrained by the folding stability. However,
little is known about the particular capacity of viral proteins to accommodate mutations that …

BACKGROUND Pregnancy loss is poorly understood, but infection may be a risk factor. Few
studies have evaluated pregnancy loss among women living with HIV in the era of potent …

BACKGROUND Childbirth via cesarean delivery can prevent intrapartum vertical
transmission for women who are not virally suppressed at the time of delivery. Few studies …

Background Molecular epidemiology techniques allow us to track the HIV-1 transmission
dynamics. Herein, we combined genetic, clinical and epidemiological data collected during …

Introduction. Human immunodeficiency virus (HIV)-1 subtype C is the most prevalent
globally and is thought to have originated in non-human primates in the Democratic …

Background Viral genomics and epidemiology have been increasingly important tools for
analysing the spread of key pathogens affecting daily lives of individuals worldwide. With the …

HIV-1 subtypes differ in their clinical manifestations and the speed in which they spread. In
particular, the frequency of subtype C is increasing relative to subtypes A and D. We …

RESUMO INTRODUÇÃO: O Vírus da Imunodeficiência Humana (HIV) é o agente etiológico
da Síndrome da Imunodeficiência Adquirida (AIDS), doença ainda sem vacina e sem cura …