In mammals, many classes of noncoding RNAs (ncRNAs) are expressed at a much higher level in the brain than in other organs. Recent studies have identified a new class of ncRNAs …
MH Bao, V Szeto, BB Yang, S Zhu, HS Sun… - Cell death & …, 2018 - nature.com
Stroke is one of the leading causes of mortality and disability worldwide. Uncovering the cellular and molecular pathophysiological processes in stroke have been a top priority. Long …
X Zhang, X Tang, K Liu, MH Hamblin… - Journal of …, 2017 - Soc Neuroscience
The study was designed to determine the role of long noncoding RNA (lncRNA), metastasis- associated lung adenocarcinoma transcript 1 (Malat1), in ischemic stroke outcome. Primary …
D Guo, J Ma, L Yan, T Li, Z Li, X Han… - Cellular Physiology and …, 2017 - karger.com
Background/Aims: LncRNA metastasis associated lung adenocarcinoma transcript 1 (MALAT1) was reported to be highly expressed in an in vitro mimic of ischemic stroke …
Background and Purpose—Adenosine in many types of RNAs can be converted to m6A (N6- methyladenosine) which is a highly dynamic epitranscriptomic modification that regulates …
K Yang, L Zeng, A Ge, S Wang, J Zeng, X Yuan… - Frontiers in …, 2022 - frontiersin.org
Cerebral infarction/ischemia-reperfusion injury is currently the disease with the highest mortality and disability rate of cardiovascular disease. Current studies have shown that …
J Wang, S Chen, W Zhang, Y Chen… - CNS Neuroscience & …, 2020 - Wiley Online Library
Aims We previously showed that the protective effects of endothelial progenitor cells (EPCs)‐ released exosomes (EPC‐EXs) on endothelium in diabetes. However, whether EPC‐EXs …
The origin story and emergence of molecular biology is muddled. The early triumphs in bacterial genetics and the complexity of animal and plant genomes complicate an intricate …
Background and Purpose—Circular RNAs (circRNAs) are a novel class of noncoding RNAs formed from many protein-coding genes by backsplicing. Although their physiological …