Molecular cytopathology for thyroid nodules: a review of methodology and test performance

M Nishino - Cancer cytopathology, 2016 - Wiley Online Library
Advances in the molecular characterization of thyroid cancers have fueled the development
of genetic and gene expression‐based tests for thyroid fine‐needle aspirations. Collectively …

Molecular profiling of thyroid nodule fine-needle aspiration cytology

M Eszlinger, L Lau, S Ghaznavi, C Symonds… - Nature Reviews …, 2017 - nature.com
The differential diagnosis and malignancy risk stratification of thyroid nodules requires
multidisciplinary expertise and knowledge of both local ultrasonography practices and the …

Fine-needle aspiration diagnoses of noninvasive follicular variant of papillary thyroid carcinoma

BE Howitt, S Chang, M Eszlinger… - American journal of …, 2015 - academic.oup.com
Objectives Endocrine pathologists are reconsidering whether tumors characterized as
noninvasive follicular variant of papillary thyroid carcinoma (NFVPTC) warrant a diagnosis of …

Impact of molecular screening for point mutations and rearrangements in routine air-dried fine-needle aspiration samples of thyroid nodules

M Eszlinger, A Krogdahl, S Münz, C Rehfeld… - Thyroid, 2014 - liebertpub.com
Background: The diagnostic limitations of thyroid fine-needle aspiration (FNA), such as the
indeterminate category, can be partially overcome by molecular analyses. However, until …

Molecular variants and their risks for malignancy in cytologically indeterminate thyroid nodules

WS Goldner, TE Angell, SL McAdoo, J Babiarz… - Thyroid, 2019 - liebertpub.com
Background: Gene panels are routinely used to assess predisposition to hereditary cancers
by simultaneously testing multiple susceptibility genes and/or variants. More recently …

Multiplatform comparison of molecular oncology tests performed on cytology specimens and formalin‐fixed, paraffin‐embedded tissue

MP Gailey, AA Stence, CS Jensen… - Cancer cytopathology, 2015 - Wiley Online Library
BACKGROUND Molecular oncology testing is important for patient management, and
requests for the molecular analysis of cytology specimens are increasingly being made …

Molecular imaging with 99mTc-MIBI and molecular testing for mutations in differentiating benign from malignant follicular neoplasm: a prospective comparison

L Giovanella, A Campenni, G Treglia… - European journal of …, 2016 - Springer
Purpose To compare mutation analysis of cytology specimens and 99m Tc-MIBI thyroid
scintigraphy for differentiating benign from malignant thyroid nodules in patients with a …

Molecular analysis of residual ThinPrep material from thyroid FNAs increases diagnostic sensitivity

JF Krane, ES Cibas, EK Alexander… - Cancer …, 2015 - Wiley Online Library
BACKGROUND Molecular testing for genetic alterations associated with malignancy is a
potential triage approach for thyroid fine‐needle aspiration (FNA) samples with …

Molecular testing of thyroid fine-needle aspirations improves presurgical diagnosis and supports the histologic identification of minimally invasive follicular thyroid …

M Eszlinger, S Piana, A Moll, E Bösenberg, A Bisagni… - Thyroid, 2015 - liebertpub.com
Background: Previous studies detecting mutations in thyroid nodule fine-needle aspiration
(FNA) material differed with respect to the cytologic grading applied to the FNAs, the type of …

[HTML][HTML] Molecular testing in the diagnosis of differentiated thyroid carcinomas

SM Ferrari, P Fallahi, I Ruffilli, G Elia, F Ragusa… - Gland …, 2018 - ncbi.nlm.nih.gov
Different genetic mutations and other molecular alterations in papillary thyroid cancer (PTC)
and follicular thyroid cancer (FTC) can be detected in fine-needle aspiration (FNA) of thyroid …