Rectal cancer treatment has evolved during the past 40 years with the use of a standardized
surgical technique for tumour resection: total mesorectal excision. A dramatic reduction in …

Background Total neoadjuvant therapy (TNT) is a novel approach for locally advanced rectal
cancer (LARC), which attempts to deliver both systemic chemotherapy and neoadjuvant …

This selection from the NCCN Guidelines for Rectal Cancer focuses on management of
malignant polyps and resectable nonmetastatic rectal cancer because important updates …

PURPOSE To ascertain if preoperative short-term radiotherapy followed by chemotherapy is
not inferior to a standard schedule of long-term chemoradiotherapy in patients with locally …

The number of deaths from colorectal cancer in Japan continues to increase. Colorectal
cancer deaths exceeded 50,000 in 2016. In the 2019 edition, revision of all aspects of …

The American Society of Colon and Rectal Surgeons (ASCRS) is dedicated to ensuring high-
quality patient care by advancing the science, prevention, and management of disorders …

The incidence of rectal cancer in the European Union is $125 000 per year, ie $35% of the
total colorectal cancer incidence, reflecting 15–25 cases/100000 population per year and is …

The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Rectal Cancer
address diagnosis, staging, surgical management, perioperative treatment, management of …

Background Radiotherapy reduces the risk of local recurrence in rectal cancer. However, the
optimal radiotherapy fractionation and interval between radiotherapy and surgery is still …

The determination of an optimal treatment plan for an individual patient with rectal cancer is
a complex process. In addition to decisions relating to the intent of rectal cancer surgery (ie …