Total volatile basic nitrogen (TVB-N) and its role in meat spoilage: A review

AEDA Bekhit, BWB Holman, SG Giteru… - Trends in Food Science & …, 2021 - Elsevier
Background Meat is a perishable product and during storage, the actions of microorganisms
and endogenous enzymes result in chemical compositional changes. Total volatile basic …

Implication of trimethylamine N-oxide (TMAO) in disease: potential biomarker or new therapeutic target

MH Janeiro, MJ Ramírez, FI Milagro, JA Martínez… - Nutrients, 2018 - mdpi.com
Trimethylamine N-oxide (TMAO) is a molecule generated from choline, betaine, and
carnitine via gut microbial metabolism. The plasma level of TMAO is determined by several …

Gut microbiota in cardiovascular health and disease

WHW Tang, T Kitai, SL Hazen - Circulation research, 2017 - Am Heart Assoc
Significant interest in recent years has focused on gut microbiota–host interaction because
accumulating evidence has revealed that intestinal microbiota play an important role in …

Microbial conversion of choline to trimethylamine requires a glycyl radical enzyme

S Craciun, EP Balskus - Proceedings of the National …, 2012 - National Acad Sciences
Choline and trimethylamine (TMA) are small molecules that play central roles in biological
processes throughout all kingdoms of life. These ubiquitous metabolites are linked through a …

[HTML][HTML] Flavoprotein monooxygenases: versatile biocatalysts

CE Paul, D Eggerichs, AH Westphal, D Tischler… - Biotechnology …, 2021 - Elsevier
Flavoprotein monooxygenases (FPMOs) are single-or two-component enzymes that
catalyze a diverse set of chemo-, regio-and enantioselective oxyfunctionalization reactions …

TMAO: A small molecule of great expectations

M Ufnal, A Zadlo, R Ostaszewski - Nutrition, 2015 - Elsevier
Trimethylamine N-oxide (TMAO) is a small organic compound whose concentration in blood
increases after ingesting dietary l-carnitine and phosphatidylcholine. Recent clinical studies …

Total volatile basic nitrogen and trimethylamine in muscle foods: Potential formation pathways and effects on human health

AEDA Bekhit, SG Giteru, BWB Holman… - … Reviews in Food …, 2021 - Wiley Online Library
The use of total volatile basic nitrogen (TVB‐N) as a quality parameter for fish is rapidly
growing to include other types of meat. Investigations of meat quality have recently focused …

Non-alcoholic fatty liver disease: pathophysiological concepts and treatment options

C Grander, F Grabherr, H Tilg - Cardiovascular Research, 2023 - academic.oup.com
The prevalence of non-alcoholic fatty liver disease (NAFLD) is continually increasing due to
the global obesity epidemic. NAFLD comprises a systemic metabolic disease accompanied …

Carnitine metabolism to trimethylamine by an unusual Rieske-type oxygenase from human microbiota

Y Zhu, E Jameson, M Crosatti… - Proceedings of the …, 2014 - National Acad Sciences
Dietary intake of l-carnitine can promote cardiovascular diseases in humans through
microbial production of trimethylamine (TMA) and its subsequent oxidation to trimethylamine …

Aerobic bacterial methane synthesis

Q Wang, A Alowaifeer, P Kerner… - Proceedings of the …, 2021 - National Acad Sciences
Reports of biogenic methane (CH4) synthesis associated with a range of organisms have
steadily accumulated in the literature. This has not happened without controversy and in …