Psoriatic arthritis is a chronic, immune-mediated, inflammatory arthropathy that presents with
inflammation of the joints and entheses, including those of the axial skeleton, and is …

Psoriasis is a common inflammatory skin disease with multiple comorbidities, including
psoriatic arthritis and coronary artery disease, that can severely impact an individual's …

Although the pathogenic mechanisms underlying axial spondyloarthritis (axSpA) and
psoriatic arthritis (PsA) are not fully elucidated, several lines of evidence suggest that …

Over the past several years, a pathophysiological role for the IL-23–IL-17 pathway in human
disease has been defined. A subset of rheumatic diseases, including psoriatic arthritis (PsA) …

Spondyloarthritis (SpA) encompasses a heterogeneous group of chronic inflammatory
diseases that can affect both axial and peripheral joints, tendons and entheses. Among the …

Pathogenic Th17 cells play important roles in many autoimmune and inflammatory diseases.
Their function depends on T cell receptor (TCR) signaling and cytokines that activate signal …

Psoriasis, an inflammatory skin disease, and psoriatic arthritis (PsA), an inflammatory
arthritis, share clinical, genetic, and pathogenic factors and may be summed as one disease …

Objective The objective for this study was to evaluate the effects of short chain fatty acids
(SCFAs) on arthritic bone remodeling. Methods We treated a recently described preclinical …

Interleukin-22 (IL-22) is secreted by a wide range of immune cells and its downstream
effects are mediated by the IL-22 receptor, which is present on non-immune cells in many …

The term spondyloarthritis (SpA) encompasses a heterogeneous group of inflammatory
musculoskeletal diseases with several common genetic background and clinical features …