Advancements in coherent Raman scattering (CRS) microscopy have enabled label-free
visualization and analysis of functional, endogenous biomolecules in living systems. When …

Lactation is a dynamic process that has evolved to produce a complex biological fluid that
provides nutritive and nonnutritive factors to the nursing offspring. It has long been assumed …

Raman spectroscopy has been recognized to be a powerful tool to study cells and tissues
because the method provides molecular information without external markers such as stains …

Cellular biomolecules contain unique molecular vibrations that can be visualized by
coherent anti-Stokes Raman scattering (CARS) microscopy without the need for labels. Here …

Molecular imaging has rapidly emerged as a discipline with the potential to impact
fundamental biomedical research and clinical practice. Within this field, optical imaging …

Because each nonlinear optical (NLO) imaging modality is sensitive to specific molecules or
structures, multimodal NLO imaging capitalizes the potential of NLO microscopy for studies …

Multiphoton microscopy (MPM) holds promise as a noninvasive imaging technique for
characterizing collagen structure, and thus mechanical properties, through imaging second …

Background Lipid-rich tumours have been associated with increased cancer metastasis and
aggressive clinical behaviours. Nonetheless, pathologists cannot classify lipid-rich tumours …

Despite the ubiquitous roles of lipids in biology, the detection of lipids has relied on invasive
techniques, population measurements, or nonspecific labeling. Such difficulties can be …

Obesity has been linked to breast cancer progression but the underlying mechanisms
remain obscure. Here we report how leptin, an obesity-associated adipokine, regulates a …