Cytotoxicity of snake venom enzymatic toxins: phospholipase A2 and l-amino acid oxidase

JJ Hiu, MKK Yap - Biochemical society transactions, 2020 - portlandpress.com
The phospholipase A2 (PLA2) and l-amino acid oxidase (LAAO) are two major enzymes
found in the venoms from most snake species. These enzymes have been structurally and …

[HTML][HTML] Snake venom L-amino acid oxidases: an overview on their antitumor effects

TR Costa, SM Burin, DL Menaldo… - Journal of Venomous …, 2014 - SciELO Brasil
The L-amino acid oxidases (LAAOs) constitute a major component of snake venoms and
have been widely studied due to their widespread presence and various effects, such as …

Biological effects of animal venoms on the human immune system

Z Avalo, MC Barrera, M Agudelo-Delgado, GJ Tobón… - Toxins, 2022 - mdpi.com
Venoms are products of specialized glands and serve many living organisms to immobilize
and kill prey, start digestive processes and act as a defense mechanism. Venoms affect …

[HTML][HTML] Antivenom activity of Moringa oleifera leave against pathophysiological alterations, somatic mutation and biological activities of Naja nigricollis venom

AO Adeyi, SB Ajisebiola, EO Adeyi, CG Alimba… - Scientific African, 2020 - Elsevier
Moringa oleifera is a plant that has several medicinal properties, however, there are dearth
of scientific information on the antivenom activities. This study therefore focused on the …

Anxiety-associated behavior and genotoxicity found in adult Danio rerio exposed to tebuconazole-based commercial product

TFD Castro, JG da Silva Souza… - Environmental …, 2018 - Elsevier
The effects of different concentrations of commercial product based on tebuconazole, on
adults of Danio rerio, were evaluated through novel tank diving test and micronucleus and …

Unraveling snake venom phospholipase A2: an overview of its structure, pharmacology, and inhibitors

GH Sampat, K Hiremath, J Dodakallanavar… - Pharmacological …, 2023 - Springer
Snake bite is a neglected disease that affects millions of people worldwide. WHO reported
approximately 5 million people are bitten by various species of snakes each year, resulting …

Purification and Biochemical Characterization of Three Myotoxins from Bothrops mattogrossensis Snake Venom with Toxicity against Leishmania and Tumor Cells

AA Moura, AM Kayano, GA Oliveira… - BioMed research …, 2014 - Wiley Online Library
Bothrops mattogrossensis snake is widely distributed throughout eastern South America and
is responsible for snakebites in this region. This paper reports the purification and …

Functional Characterization and Anti-Tumor Effect of a Novel Group II Secreted Phospholipase A2 from Snake Venom of Saudi Cerastes cerates gasperetti

M Alonazi, N Krayem, MG Alharbi, AIA Khayyat… - Molecules, 2023 - mdpi.com
Secreted phospholipases A2 are snake-venom proteins with many biological activities,
notably anti-tumor activity. Phospholipases from the same snake type but different …

A review on genotoxic and genoprotective effects of biologically active compounds of animal origin

N Sjakste, G Gajski - Toxins, 2023 - mdpi.com
Envenomation by animal venoms remains a serious medical and social problem, especially
in tropical countries. On the other hand, animal venoms are widely used as a source of …

BmajPLA2-II, a basic Lys49-phospholipase A2 homologue from Bothrops marajoensis snake venom with parasiticidal potential

AN Grabner, J Alfonso, AM Kayano… - International journal of …, 2017 - Elsevier
Snake venoms contain various proteins, especially phospholipases A 2 (PLA 2 s), which
present potential applications in diverse areas of health and medicine. In this study, a new …