Towards precision medicine

EA Ashley - Nature Reviews Genetics, 2016 - nature.com
There is great potential for genome sequencing to enhance patient care through improved
diagnostic sensitivity and more precise therapeutic targeting. To maximize this potential …

From data to knowledge: the future of multi-omics data analysis for the rhizosphere

RA White, MI Borkum, A Rivas-Ubach, A Bilbao… - Rhizosphere, 2017 - Elsevier
The rhizosphere is the interface between the root system of a plant and its surrounding soil.
The microbiome of the rhizosphere, which is the totality of all microbes present there …

A chromosome‐level genome assembly reveals the genetic basis of cold tolerance in a notorious rice insect pest, Chilo suppressalis

W Ma, X Zhao, C Yin, F Jiang, X Du… - Molecular Ecology …, 2020 - Wiley Online Library
The rice stem borer, Chilo suppressalis, is one of the most damaging insect pests to rice
production worldwide. Although C. suppressalis has been the focus of numerous studies …

Graphical pangenomics

E Garrison - 2019 - repository.cam.ac.uk
Completely sequencing genomes is expensive, and to save costs we often analyze new
genomic data in the context of a reference genome. This approach distorts our image of the …

Distributed RMI-DBG model: Scalable iterative de Bruijn graph algorithm for short read genome assembly problem

ZZ Hosseini, SK Rahimi, E Forouzan… - Expert Systems with …, 2023 - Elsevier
Genome assembly is the computational process of merging short parts of DNA into larger
sequences called contigs. Rapid growth of high-throughput genome sequencing …

An efficient error correction algorithm using fm-index

YT Huang, YW Huang - BMC bioinformatics, 2017 - Springer
Background High-throughput sequencing offers higher throughput and lower cost for
sequencing a genome. However, sequencing errors, including mismatches and indels, may …

Analysis method and algorithm design of biological sequence problem based on generalized k-mer vector

W Liu, Q Wu - Applied Mathematics-A Journal of Chinese Universities, 2021 - Springer
K-mer can be used for the description of biological sequences and k-mer distribution is a
tool for solving sequences analysis problems in bioinformatics. We can use k-mer vector as …

RMI-DBG algorithm: A more agile iterative de Bruijn graph algorithm in short read genome assembly

ZZ Hosseini, SK Rahimi, E Forouzan… - Journal of Bioinformatics …, 2021 - World Scientific
The de Bruijn Graph algorithm (DBG) as one of the cornerstones algorithms in short read
assembly has extended with the rapid advancement of the Next Generation Sequencing …

DRAGoM: classification and quantification of noncoding RNA in metagenomic data

B Liu, S Thippabhotla, J Zhang, C Zhong - Frontiers in Genetics, 2021 - frontiersin.org
Noncoding RNAs (ncRNAs) play important regulatory and functional roles in
microorganisms, such as regulation of gene expression, signaling, protein synthesis, and …

The representation of n-cutting site splicing languages for a single string with palindromic rule via de Bruijn graph

NM Ruslim, Y Yusof, MS Mohamad - AIP Conference Proceedings, 2024 - pubs.aip.org
Yusof-Goode (YG) splicing system proposed by Yusof illustrates the deoxyribonucleic acid
(DNA) splicing process in a luminous way, where the rule is written in a double triple …