Recent advancements in typical friedel–crafts alkylation reactions focused on targeting arene nucleophiles

S Singh, CK Hazra - Synthesis, 2024 - thieme-connect.com
This review delves into recent advances and significant breakthroughs in the field of the
catalytic Friedel–Crafts alkylation of targeted arenes or heteroarenes. Though a few earlier …

A recent update on the environment friendly methodologies to synthesize bis (indolyl) methane and 3, 3-di (3-indolyl)-2-indolone derivatives

P Kamboj, V Tyagi - Tetrahedron, 2023 - Elsevier
Indole, widely recognized as a versatile category of heterocyclic frameworks that contain
nitrogen is extensively employed in the synthesis of various organic compounds due to their …

Review on Catalytic Meinwald Rearrangement of Epoxides

Y Zhang, B Hu, Y Chen, Z Wang - Chemistry–A European …, 2024 - Wiley Online Library
The past few decades have witnessed tremendous development within epoxides. Among
the many known reactions involving epoxide, Meinwald rearrangements represent one of …

Synthesis of Azepinoindoles and Oxepinoindoles through Brønsted-Acid-Catalyzed Cyclization of an In Situ Generated Dihydrospiroquinoline Intermediate

R Mahato, N Yadav, CK Hazra - Organic Letters, 2024 - ACS Publications
We have developed a straightforward and efficient synthetic protocol to produce 5, 6, 7, 12-
tetrahydrobenzo [2, 3] azepino [4, 5-b] indole and 7, 12-dihydro-6 H-benzo [2, 3] oxepino [4 …

Nondirected Ortho C–H Arylation for One-Pot Synthesis of Biaryl Scaffolds via In Situ Generated Mixed Acetal

A Tyagi, H Gautam, K Tripathi… - The Journal of Organic …, 2024 - ACS Publications
Herein, we introduce a mild and efficient method for synthesizing aniline biaryls and
unsymmetrical phenol biaryls through iodine-catalyzed coupling of quinone imine ketals …

Effect of N-heterocyclic carbene in palladium–tin heterobimetallic catalysis: a DFT supported study on the C3–H functionalization of unprotected indoles

MK Nayak, RR Maharana, A Mohanty… - Catalysis Science & …, 2024 - pubs.rsc.org
A new N-heterocyclic carbene (NHC)-based Pd–Sn heterobimetallic complex [(NHC) Pd (μ-
Br) SnCl3] 2 with low steric crowding in the active catalytic region was designed. The …

Silane‐Mediated Alkylation of Arenes via Reductive Friedel‐Crafts Reaction Using Carbonyl Compounds

J Khan, R Mahato, Kanhaiya… - Asian Journal of …, 2024 - Wiley Online Library
A metal‐free one‐pot synthesis route has been documented for the production of 1, 1‐
unsymmetrical di‐aryl alkanes via reductive Friedel− Crafts alkylation of arenes with …

Lewis Acid Promoted Homodimerization of Styrene Diols: An Efficient Approach toward 2-Phenylnaphthalenes

R Mahato, J Khan, A Tyagi, CK Hazra - Synlett, 2023 - thieme-connect.com
We report a straightforward, metal-free, efficient protocol for the synthesis of 2-
phenylnaphthalenes from 1-phenylethane-1, 2-diols under mild conditions. In this strategy …

Lewis Acid-catalyzed Regioselective Addition of Allenoates to Indoles for Synthesis of Bisindolylesters

F Xie, J He, Y Zhang - Chemical Research in Chinese Universities, 2024 - Springer
Indole derivatives, especially bisindolylesters, have attracted intense attention due to their
important applications in medicinal chemistry and organic synthesis. Here we develop a …

Three-membered ring systems

JS Russel - Progress in Heterocyclic Chemistry, 2024 - Elsevier
This chapter is a survey of the synthesis and reactions of three-membered heterocycles
reported during 2022. Primary emphasis has been devoted to the chemistry of epoxides …