During tumor progression, circulating monocytes and macrophages are actively recruited
into tumors where they alter the tumor microenvironment to accelerate tumor progression …

The mechanisms responsible for recruiting monocytes from the bloodstream into solid
tumors are now well characterized. However, recent evidence has shown that these cells …

Developing tumors rapidly outgrow their oxygen supply and are subject to hypoxia, which
stimulates hypersecretion of tumor-derived exosomes that promote angiogenesis …

The immunogenicity of malignant cells has recently been acknowledged as a critical
determinant of efficacy in cancer therapy. Thus, besides developing direct …

Immunogenic profile of certain cancer cell death mechanisms has been transmuted by
research published over a period of last few years and this change has been so drastic that …

Over the course of evolution, eukaryotic aminoacyl-tRNA synthetases (aaRSs) progressively
incorporated domains and motifs that have no essential connection to aminoacylation …

Cells undergoing apoptosis are efficiently located and engulfed by phagocytes. The
mechanisms by which macrophages, the professional scavenging phagocytes of apoptotic …

To form a diffusible interface large enough to conduct respiratory gas exchange with the
circulation, the lung endoderm undergoes extensive branching morphogenesis and …

Ischemia followed by reperfusion leads to severe organ injury and dysfunction. Inflammation
is considered to be the most important cause of tissue injury in organs subjected to …

Macrophage-mediated segmental demyelination is the pathological hallmark of autoimmune
demyelinating polyneuropathies, including the demyelinating form of Guillain-Barré …