The human virome: assembly, composition and host interactions

G Liang, FD Bushman - Nature Reviews Microbiology, 2021 - nature.com
The human body hosts vast microbial communities, termed the microbiome. Less well
known is the fact that the human body also hosts vast numbers of different viruses …

Revisiting the rules of life for viruses of microorganisms

AMS Correa, C Howard-Varona, SR Coy… - Nature Reviews …, 2021 - nature.com
Viruses that infect microbial hosts have traditionally been studied in laboratory settings with
a focus on either obligate lysis or persistent lysogeny. In the environment, these infection …

Phage combination therapies for bacterial wilt disease in tomato

X Wang, Z Wei, K Yang, J Wang, A Jousset, Y Xu… - Nature …, 2019 - nature.com
Bacteriophages have been proposed as an alternative to pesticides to kill bacterial
pathogens of crops. However, the efficacy of phage biocontrol is variable and poorly …

Microbial defenses against mobile genetic elements and viruses: Who defends whom from what?

EPC Rocha, D Bikard - PLoS biology, 2022 - journals.plos.org
Prokaryotes have numerous mobile genetic elements (MGEs) that mediate horizontal gene
transfer (HGT) between cells. These elements can be costly, even deadly, and cells use …

Organochlorine contamination enriches virus-encoded metabolism and pesticide degradation associated auxiliary genes in soil microbiomes

X Zheng, MT Jahn, M Sun, VP Friman… - The ISME …, 2022 - academic.oup.com
Viruses significantly influence local and global biogeochemical cycles and help bacteria to
survive in different environments by encoding various auxiliary metabolic genes (AMGs) …

The Role of Pseudomonas aeruginosa Lipopolysaccharide in Bacterial Pathogenesis and Physiology

SM Huszczynski, JS Lam, CM Khursigara - Pathogens, 2019 - mdpi.com
The major constituent of the outer membrane of Gram-negative bacteria is
lipopolysaccharide (LPS), which is comprised of lipid A, core oligosaccharide, and O …

[HTML][HTML] New insights into intestinal phages

R Sausset, MA Petit, V Gaboriau-Routhiau… - Mucosal …, 2020 - Elsevier
The intestinal microbiota plays important roles in human health. This last decade, the viral
fraction of the intestinal microbiota, composed essentially of phages that infect bacteria …

Antibiotic Resistance Profiles, Molecular Mechanisms and Innovative Treatment Strategies of Acinetobacter baumannii

CO Vrancianu, I Gheorghe, IB Czobor, MC Chifiriuc - Microorganisms, 2020 - mdpi.com
Antibiotic resistance is one of the biggest challenges for the clinical sector and industry,
environment and societal development. One of the most important pathogens responsible …

Selfish, promiscuous and sometimes useful: how mobile genetic elements drive horizontal gene transfer in microbial populations

M Haudiquet, JM de Sousa… - … Transactions of the …, 2022 - royalsocietypublishing.org
Horizontal gene transfer (HGT) drives microbial adaptation but is often under the control of
mobile genetic elements (MGEs) whose interests are not necessarily aligned with those of …

Bacteriophages avoid autoimmunity from cognate immune systems as an intrinsic part of their life cycles

JT Rostøl, N Quiles-Puchalt, P Iturbe-Sanz, Í Lasa… - Nature …, 2024 - nature.com
Dormant prophages protect lysogenic cells by expressing diverse immune systems, which
must avoid targeting their cognate prophages upon activation. Here we report that multiple …