Spatial proteomics for the molecular characterization of breast cancer
Breast cancer (BC) is a major global health issue, affecting a significant proportion of the
female population and contributing to high rates of mortality. One of the primary challenges …
female population and contributing to high rates of mortality. One of the primary challenges …
Correlative multi-modal microscopy: a novel pipeline for optimizing fluorescence microscopy resolutions in biological applications
The modern fluorescence microscope is the convergence point of technologies with different
performances in terms of statistical sampling, number of simultaneously analyzed signals …
performances in terms of statistical sampling, number of simultaneously analyzed signals …
Recent advancements in tumour microenvironment landscaping for target selection and response prediction in immune checkpoint therapies achieved through spatial …
Immune checkpoint therapies have significantly advanced cancer treatment. Nevertheless,
the high costs and potential adverse effects associated with these therapies highlight the …
the high costs and potential adverse effects associated with these therapies highlight the …
Quantitative multiplex immunohistochemistry with colorimetric staining (QUIVER) may still benefit from MILAN
Cyclic multiplex immunostaining consists of cycles of staining, imaging, removal of the signal
and repetition with another set of antibodies. Removal of the primary and secondary …
and repetition with another set of antibodies. Removal of the primary and secondary …
A DNA damage response‐like phenotype defines a third of colon cancers at onset
S Mauro, MM Bolognesi, N Villa, G Capitoli… - The FASEB …, 2023 - Wiley Online Library
Colon adenocarcinoma (COAD) has a limited range of diversified, personalized therapeutic
opportunities, besides DNA hypermutating cases; thus, both new targets or broadening …
opportunities, besides DNA hypermutating cases; thus, both new targets or broadening …
Seeing or believing in hyperplexed spatial proteomics via antibodies: New and old biases for an image-based technology
Hyperplexed in-situ targeted proteomics via antibody immunodetection (ie,> 15 markers) is
changing how we classify cells and tissues. Differently from other high-dimensional single …
changing how we classify cells and tissues. Differently from other high-dimensional single …