Targeting tumor necrosis factor alpha for Alzheimer's disease

B Decourt, DK Lahiri… - Current Alzheimer …, 2017 - ingentaconnect.com
Alzheimer's disease (AD) affects an estimated 44 million individuals worldwide, yet no
therapeutic intervention is available to stop the progression of the dementia …

Exercise programs for people with dementia

D Forbes, SC Forbes, CM Blake… - Cochrane database …, 2015 - cochranelibrary.com
Background This is an update of our previous 2013 review. Several recent trials and
systematic reviews of the impact of exercise on people with dementia are reporting …

Effects of physical activity and exercise on the cognitive function of patients with Alzheimer disease: a meta-analysis

R Jia, J Liang, Y Xu, Y Wang - BMC geriatrics, 2019 - Springer
Background Alzheimer's disease (AD), as the most common cause of dementia, brings huge
economic burden for patients and social health care systems, which motivates researchers …

Physical exercise improves quality of life, depressive symptoms, and cognition across chronic brain disorders: a transdiagnostic systematic review and meta-analysis …

M Dauwan, MJH Begemann, MIE Slot, EHM Lee… - Journal of …, 2021 - Springer
We performed a meta-analysis to synthesize evidence on the efficacy and safety of physical
exercise as an add-on therapeutic intervention for quality of life (QoL), depressive symptoms …

Physical exercise and cognitive performance in the elderly: current perspectives

NJ Kirk-Sanchez, EL McGough - Clinical interventions in aging, 2014 - Taylor & Francis
In an aging population with increasing incidence of dementia and cognitive impairment,
strategies are needed to slow age-related decline and reduce disease-related cognitive …

[HTML][HTML] Physical exercise improves strength, balance, mobility, and endurance in people with cognitive impairment and dementia: a systematic review

FMH Lam, MZ Huang, LR Liao, RCK Chung… - Journal of …, 2018 - Elsevier
Question Does physical exercise training improve physical function and quality of life in
people with cognitive impairment and dementia? Which training protocols improve physical …

Exercise interventions in Alzheimer's disease: A systematic review and meta-analysis of randomized controlled trials

S Lopez-Ortiz, PL Valenzuela, MM Seisdedos… - Ageing Research …, 2021 - Elsevier
Aims To assess the potential multi-domain benefits of exercise interventions on patients with
Alzheimer's disease (AD), as well as to determine the specific effects of different exercise …

Effects of the Finnish Alzheimer disease exercise trial (FINALEX): a randomized controlled trial

KH Pitkälä, MM Pöysti, ML Laakkonen… - JAMA internal …, 2013 - jamanetwork.com
Importance Few rigorous clinical trials have investigated the effectiveness of exercise on the
physical functioning of patients with Alzheimer disease (AD). Objectives To investigate the …

Implications for public health research of models and theories of disability: a scoping study and evidence synthesis

MJ Berghs, KM Atkin, HM Graham, C Hatton, C Thomas - 2016 - eprints.whiterose.ac.uk
Implications for public health research of models and theories of disability : a scoping study
and evidence synthesis Page 1 This is a repository copy of Implications for public health …

Genetic mouse models of brain ageing and Alzheimer's disease

A Bilkei-Gorzo - Pharmacology & therapeutics, 2014 - Elsevier
Progression of brain ageing is influenced by a complex interaction of genetic and
environmental factors. Analysis of genetically modified animals with uniform genetic …