Factor XIII (FXIII) is a transglutaminase enzyme that catalyses the formation of ε-(γ-glutamyl)
lysyl isopeptide bonds into protein substrates. The plasma form, FXIIIA2B2, has an …

Trauma is responsible for 1 in 10 deaths worldwide and is the leading cause of death of
people less than 45 years old. 1 The two most common causes of death in trauma victims …

For creating functional tissue analogues in tissue engineering, stem cells require very
specific 3D microenvironments to thrive and mature. Demanding (stem) cell types that are …

Arterial and venous thromboses are major contributors to coagulation-associated morbidity
and mortality. Greater understanding of mechanisms leading to thrombus formation and …

Background: The fatal consequences of an infection with severe acute respiratory syndrome
coronavirus 2 are not only caused by severe pneumonia, but also by thrombosis. Platelets …

The formation and dissolution of blood clots is both a biochemical and a biomechanical
process. While much of the chemistry has been worked out for both processes, the influence …

Atherothrombosis is a leading cause of cardiovascular mortality and long-term morbidity.
Platelets and coagulation proteases, interacting with circulating cells and in different …

Simple Summary The risk of venous thromboembolism in cancer is nine times higher than in
the general population and the second leading cause of death in these patients. Tissue …

Acute traumatic coagulopathy (ATC) is the failure of coagulation homeostasis that can
rapidly arise following traumatic injury, hemorrhage, and shock; it is associated with higher …

Background Vaccine-induced immune thrombocytopenia and thrombosis (VITT) is a rare
syndrome associated with adenoviral vector vaccines for COVID-19. The syndrome is …