Anatomy and Physiology of the Digestive Tract of Drosophila melanogaster

I Miguel-Aliaga, H Jasper, B Lemaitre - Genetics, 2018 - academic.oup.com
The gastrointestinal tract has recently come to the forefront of multiple research fields. It is
now recognized as a major source of signals modulating food intake, insulin secretion and …

Drosophila tools and assays for the study of human diseases

B Ugur, K Chen, HJ Bellen - Disease models & mechanisms, 2016 - journals.biologists.com
Many of the internal organ systems of Drosophila melanogaster are functionally analogous
to those in vertebrates, including humans. Although humans and flies differ greatly in terms …

FlyBase: a guided tour of highlighted features

LS Gramates, J Agapite, H Attrill, BR Calvi… - Genetics, 2022 - academic.oup.com
FlyBase provides a centralized resource for the genetic and genomic data of Drosophila
melanogaster. As FlyBase enters our fourth decade of service to the research community …

Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly

H Li, J Janssens, M De Waegeneer, SS Kolluru… - Science, 2022 - science.org
For more than 100 years, the fruit fly Drosophila melanogaster has been one of the most
studied model organisms. Here, we present a single-cell atlas of the adult fly, Tabula …

FlyBase: updates to the Drosophila melanogaster knowledge base

A Larkin, SJ Marygold, G Antonazzo… - Nucleic acids …, 2021 - academic.oup.com
FlyBase (flybase. org) is an essential online database for researchers using Drosophila
melanogaster as a model organism, facilitating access to a diverse array of information that …

FlyAtlas 2: a new version of the Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

DP Leader, SA Krause, A Pandit… - Nucleic acids …, 2018 - academic.oup.com
Abstract FlyAtlas 2 (www. flyatlas2. org) is part successor, part complement to the FlyAtlas
database and web application for studying the expression of the genes of Drosophila …

Genome-wide analysis of drosophila circular RNAs reveals their structural and sequence properties and age-dependent neural accumulation

JO Westholm, P Miura, S Olson, S Shenker, B Joseph… - Cell reports, 2014 - cell.com
Circularization was recently recognized to broadly expand transcriptome complexity. Here,
we exploit massive Drosophila total RNA-sequencing data,> 5 billion paired-end reads …

High-resolution 3D spatiotemporal transcriptomic maps of developing Drosophila embryos and larvae

M Wang, Q Hu, T Lv, Y Wang, Q Lan, R Xiang, Z Tu… - Developmental Cell, 2022 - cell.com
Drosophila has long been a successful model organism in multiple biomedical fields. Spatial
gene expression patterns are critical for the understanding of complex pathways and …

Recent advances in neuropeptide signaling in Drosophila, from genes to physiology and behavior

DR Nässel, M Zandawala - Progress in neurobiology, 2019 - Elsevier
This review focuses on neuropeptides and peptide hormones, the largest and most diverse
class of neuroactive substances, known in Drosophila and other animals to play roles in …

A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff: SNPs in the genome of Drosophila melanogaster strain w1118; iso-2; …

P Cingolani, A Platts, LL Wang, M Coon, T Nguyen… - fly, 2012 - Taylor & Francis
We describe a new computer program, SnpEff, for rapidly categorizing the effects of variants
in genome sequences. Once a genome is sequenced, SnpEff annotates variants based on …