[HTML][HTML] Are synthetic glucocorticoids in the aquatic environment a risk to fish?

CM Hamilton, MJ Winter, L Margiotta-Casaluci… - Environment …, 2022 - Elsevier
The glucocorticosteroid, or glucocorticoid (GC), system is largely conserved across
vertebrates and plays a central role in numerous vital physiological processes including …

Glucocorticoids in fish eggs: variation, interactions with the environment, and the potential to shape offspring fitness

NM Sopinka, PM Capelle… - Physiological and …, 2017 - journals.uchicago.edu
Wild and captive vertebrates face multiple stressors that all have the potential to induce
chronic maternal stress (ie, sustained, elevated plasma glucocorticoids), resulting in embryo …

Occurrence of glucocorticoids, mineralocorticoids, and progestogens in various treated wastewater, rivers, and streams

A Weizel, MP Schlüsener, G Dierkes… - … science & technology, 2018 - ACS Publications
In the current study a high sensitive analytical method was developed for the determination
of 60 steroids including glucocorticoids (GC), mineralocorticoids (MC), and progestogens …

[HTML][HTML] Determination and occurrence of natural and synthetic glucocorticoids in surface waters

X Shen, H Chang, Y Sun, Y Wan - Environment international, 2020 - Elsevier
Glucocorticoids (GCs) have been increasingly reported to have adverse effects on aquatic
organisms, but the lack of comprehensive analytical methods for a broad number of GCs has …

[HTML][HTML] Emerging concepts and opportunities for endocrine disruptor screening of the non-EATS modalities

CJ Martyniuk, R Martínez, L Navarro-Martín… - Environmental …, 2022 - Elsevier
Endocrine disrupting chemicals (EDCs) are ubiquitous in the environment and involve
diverse chemical-receptor interactions that can perturb hormone signaling. The Organization …

Occurrence and ecotoxicological effects of free, conjugated, and halogenated steroids including 17α-hydroxypregnanolone and pregnanediol in Swiss wastewater …

K Zhang, Y Zhao, K Fent - Environmental science & technology, 2017 - ACS Publications
Apart from estrogens, the occurrence and ecotoxicity of steroids in aquatic environments is
poorly known. Here, we analyzed 33 steroids, including estrogens, androgens, progestins …

Toxicity prediction and effect characterization of 90 pharmaceuticals and illicit drugs measured in plasma of fish from a major European river (Sava, Croatia)

O Malev, M Lovrić, D Stipaničev, S Repec… - Environmental …, 2020 - Elsevier
Chemical analysis of plasma samples of wild fish from the Sava River (Croatia) revealed the
presence of 90 different pharmaceuticals/illicit drugs and their metabolites (PhACs/IDrgs) …

Active glucocorticoids have a range of important adverse developmental and physiological effects on developing zebrafish embryos

RA Willi, S Faltermann, T Hettich… - Environmental science & …, 2018 - ACS Publications
Glucocorticoids in aquatic systems originating from natural excretion and medical use may
pose a risk to fish. Here, we analyzed physiological and transcriptional effects of clobetasol …

Occurrence, distribution, and potential risks of environmental corticosteroids in surface waters from the Pearl River Delta, South China

J Gong, C Lin, X Xiong, D Chen, Y Chen, Y Zhou… - Environmental …, 2019 - Elsevier
The occurrence, spatiotemporal distribution, and potential risks of 21 glucocorticoids (GCs)
and 3 mineralocorticoids (MCs) in four rivers were studied by investigating the surface …

[HTML][HTML] Glucocorticoid mixtures of fluticasone propionate, triamcinolone acetonide and clobetasol propionate induce additive effects in zebrafish embryos

RA Willi, N Salgueiro-González, G Carcaiso… - Journal of hazardous …, 2019 - Elsevier
Many synthetic glucocorticoids from medical applications occur in the aquatic environment.
Whether they pose a risk for fish health is poorly known. Here we investigate effects of …