Mobile genetic element flexibility as an underlying principle to bacterial evolution

AJ Weisberg, JH Chang - Annual Review of Microbiology, 2023 - annualreviews.org
Mobile genetic elements are key to the evolution of bacteria and traits that affect host and
ecosystem health. Here, we use a framework of a hierarchical and modular system that …

Antibiotic resistance in Pseudomonas aeruginosa–Mechanisms, epidemiology and evolution

J Botelho, F Grosso, L Peixe - Drug resistance updates, 2019 - Elsevier
Antibiotics are powerful drugs used in the treatment of bacterial infections. The inappropriate
use of these medicines has driven the dissemination of antibiotic resistance (AR) in most …

Rhizobia: from saprophytes to endosymbionts

P Poole, V Ramachandran, J Terpolilli - Nature Reviews Microbiology, 2018 - nature.com
Rhizobia are some of the best-studied plant microbiota. These oligotrophic
Alphaproteobacteria or Betaproteobacteria form symbioses with their legume hosts …

ICEberg 2.0: an updated database of bacterial integrative and conjugative elements

M Liu, X Li, Y Xie, D Bi, J Sun, J Li, C Tai… - Nucleic acids …, 2019 - academic.oup.com
Abstract ICEberg 2.0 (http://db-mml. sjtu. edu. cn/ICEberg/) is an updated database that
provides comprehensive information about bacterial integrative and conjugative elements …

The role of integrative and conjugative elements in antibiotic resistance evolution

J Botelho, H Schulenburg - Trends in microbiology, 2021 - cell.com
Mobile genetic elements (MGEs), such as plasmids and integrative and conjugative
elements (ICEs), are main drivers for the spread of antibiotic resistance (AR). Coevolution …

The hidden life of integrative and conjugative elements

F Delavat, R Miyazaki, N Carraro… - FEMS microbiology …, 2017 - academic.oup.com
Integrative and conjugative elements (ICEs) are widespread mobile DNA that transmit both
vertically, in a host-integrated state, and horizontally, through excision and transfer to new …

Horizontal transfer of symbiosis genes within and between rhizobial genera: occurrence and importance

M Andrews, S De Meyer, EK James, T Stępkowski… - Genes, 2018 - mdpi.com
Rhizobial symbiosis genes are often carried on symbiotic islands or plasmids that can be
transferred (horizontal transfer) between different bacterial species. Symbiosis genes …

A systematic approach to classify and characterize genomic islands driven by conjugative mobility using protein signatures

B Audrey, N Cellier, F White, PÉ Jacques… - Nucleic Acids …, 2023 - academic.oup.com
Genomic islands (GIs) play a crucial role in the spread of antibiotic resistance, virulence
factors and antiviral defense systems in a broad range of bacterial species. However, the …

Why are rhizobial symbiosis genes mobile?

GE Wardell, MF Hynes, PJ Young… - … Transactions of the …, 2022 - royalsocietypublishing.org
Rhizobia are one of the most important and best studied groups of bacterial symbionts. They
are defined by their ability to establish nitrogen-fixing intracellular infections within plant …

Global-level population genomics reveals differential effects of geography and phylogeny on horizontal gene transfer in soil bacteria

A Greenlon, PL Chang, ZM Damtew… - Proceedings of the …, 2019 - National Acad Sciences
Although microorganisms are known to dominate Earth's biospheres and drive
biogeochemical cycling, little is known about the geographic distributions of microbial …