Metronidazole, a nitroimidazole, remains a front-line choice for treatment of infections
related to inflammatory disorders of the gastrointestinal tract including colitis linked to …

Metronidazole has been used for the treatment of infections for> 45 years and is still
successfully used for the treatment of trichomoniasis, amoebiasis, and giardiasis. Anaerobic …

Objectives: Human clinical isolates of Bacteroides spp. originating from patients in the UK
were investigated for the presence of metronidazole resistance determinants (nim genes) …

Nitroimidazole resistance (nim) genes were detected in 2% of 1,502 clinical Bacteroides
fragilis group strains isolated from 19 European countries, and a novel nim gene was …

The advent of the human immunodeficiency virus infection and the increasing prevalence of
compromised individuals in the community due to modern therapeutic advances have …

5-Nitroimidazole-based antibiotics are compounds extensively used for treating infections in
humans and animals caused by several important pathogens. They are administered as …

Objectives: The current work focused on molecular changes in a spontaneous Bacteroides
fragilis mutant selected by low concentrations of metronidazole as an adaptive response to …

Nonduplicate clinical isolates of Prevotella spp. recovered from patients hospitalized
between 2003 and 2006 in two French tertiary-care teaching hospitals were investigated for …

Abstract Background The prevalence of Bacteroides fragilis isolates resistant to first-line
beta-lactam drugs is increasing, resulting in reduced treatment efficacy. Investigating the …

Background: Bacteroides fragilis is the most common anaerobic pathogen isolated from
surgical site infections (SSIs). Metronidazole resistance is increasing and the mechanisms of …