Hyperosmolar therapy is regarded as the mainstay for treatment of elevated intracranial
pressure (ICP) in traumatic brain injury (TBI). This still has been disputed as application of …

Background Acute treatment of cerebral edema and elevated intracranial pressure is a
common issue in patients with neurological injury. Practical recommendations regarding …

Background: Mannitol and hypertonic saline are widely used to treat raised intracranial
pressure (ICP) after traumatic brain injury (TBI), but the clinical superiority of one over the …

Background: To compare the effects of 3% hypertonic saline solution and 20% mannitol
solution on intracranial hypertension. Methods: WAN-FANGDATA, CNKI, and CQVIP …

Increased intracranial pressure (ICP) can be a medical or surgical emergency. 1 Both
intracranial and systemic events contribute to increased ICP after traumatic brain injury (TBI) …

The population of elderly individuals is increasing worldwide. With aging, various hormonal
and kidney changes occur, both affecting water homeostasis. Aging is a risk factor for …

Background Intravenous hypertonic saline is utilized commonly in critical care for treatment
of acute or refractory elevations of intracranial pressure (ICP) in traumatic brain injury (TBI) …

Introduction The optimal approach to fluid management in critically ill patients is highly
debated. Fluid resuscitation using hypertonic saline was used in the past for more than thirty …

Increased intracranial pressure (ICP) is one of the most important modifiable and immediate
threats to critically ill patients suffering from traumatic brain injury (TBI). Two hyperosmolar …

The purpose of this study was to establish a rat asthma model and extract MUC5AC to
explore the mechanism of mucin 5AC (MUC5AC) signaling pathway regulating the function …