The bones of children with obesity

D Fintini, S Cianfarani, M Cofini, A Andreoletti… - Frontiers in …, 2020 - frontiersin.org
Excess adiposity in childhood may affect bone development, ultimately leading to bone
frailty. Previous reports showing an increased rate of extremity fractures in children with …

Relationship between non-alcoholic fatty liver disease and degree of hepatic steatosis and bone mineral density

R Xie, M Liu - Frontiers in Endocrinology, 2022 - frontiersin.org
Background The liver and bones are both active endocrine organs that carry out several
metabolic functions. However, the link between non-alcoholic fatty liver disease (NAFLD) …

Bone turnover markers in children: from laboratory challenges to clinical interpretation

A Ladang, F Rauch, E Delvin, E Cavalier - Calcified tissue international, 2023 - Springer
Bone turnover markers (BTMs) have been developed many years ago to study, in
combination with imaging techniques, bone remodeling in adults. In children and …

Positive association between high-density lipoprotein cholesterol and bone mineral density in US adults: the NHANES 2011–2018

R Xie, X Huang, Q Liu, M Liu - Journal of Orthopaedic Surgery and …, 2022 - Springer
Background Serum lipids are highly inheritable and play a major role in bone health.
However, the relationship between high-density lipoprotein cholesterol (HDL-C) and bone …

High-density lipoprotein cholesterol is negatively correlated with bone mineral density and has potential predictive value for bone loss

Y Tang, S Wang, Q Yi, Y Xia, B Geng - Lipids in health and disease, 2021 - Springer
Background Many studies have shown that lipids play important roles in bone metabolism.
However, the association between high-density lipoprotein cholesterol (HDL-C) and bone …

Children and adolescents with obesity have reduced serum bone turnover markers and 25-hydroxyvitamin D but increased parathyroid hormone concentrations …

M Geserick, M Vogel, F Eckelt, M Schlingmann… - Bone, 2020 - Elsevier
Background We aimed to establish age-and gender-specific reference ranges for
concentrations of the bone markers osteocalcin (OC), procollagen type 1 N-propeptides …

Serum concentration of asprosin in new-onset type 2 diabetes

S Naiemian, M Naeemipour, M Zarei… - Diabetology & Metabolic …, 2020 - Springer
Background Asprosin, a newly identified adipokine, is pathologically increased in
individuals with insulin resistance. However, the available evidence on the association of …

The saturation effect of obesity on bone Mineral density for older people: the NHANES 2017–2020

Y Zhang, J Pu - Frontiers in Endocrinology, 2022 - frontiersin.org
Introduction Previous studies have shown that obesity has a positive effect on bone mineral
density (BMD). However, excessive obesity is harmful to health, especially in older adults. In …

High low-density lipoprotein cholesterol levels are associated with osteoporosis among adults 20–59 years of age

R Xie, X Huang, Y Zhang, Q Liu… - International Journal of …, 2022 - Taylor & Francis
Background Serum lipids are highly inheritable and play a major role in bone health.
However, the relationship between low-density lipoprotein cholesterol (LDL-C) and bone …

Children as biomarker orphans: progress in the field of pediatric biomarkers

DR Shores, AD Everett - The Journal of pediatrics, 2018 - jpeds.com
Biomarkers are incorporated ubiquitously into clini-cal practice as surrogate endpoints of
physiologic and pathologic processes that cannot be measured directly. For example, a lipid …