Abnormal placentation is considered as an underlying cause of various pregnancy
complications such as miscarriage, preeclampsia and intrauterine growth restriction, the …

The placenta is the chief regulator of nutrient supply to the growing embryo during gestation.
As such, adequate placental function is instrumental for developmental progression …

The past decade has seen a substantial advancement in our understanding of placental
diseases that are associated with fetal growth restriction (FGR). 1 This increased …

The placenta is a transient organ that forms during pregnancy to support the growth and
development of the fetus. During human placental development, trophoblast cells …

Mechanisms of implantation such as determination of the attachment pole, fetal-maternal
communication, and underlying causes of implantation failure are largely unexplored. Here …

Wingless ligands, a family of secreted proteins, are critically involved in organ development
and tissue homeostasis by ensuring balanced rates of stem cell proliferation, cell death and …

Remodeling of the uterine vasculature by invasive extravillous trophoblasts (EVTs) is a
critical aspect of human placentation. Insufficient EVT invasion can lead to severe obstetrical …

Traditionally, the mouse has been the favoured vertebrate model for biomedical research,
due to its experimental and genetic tractability. However, non-rodent embryological studies …

Placentation is a reproductive adaptation that permits fetal growth and development within
the protected confines of the female reproductive tract. Through this important role, the …

Various pregnancy complications, such as severe forms of preeclampsia or intrauterine
growth restriction, are thought to arise from failures in the differentiation of human placental …