Transforming growth factor-β-induced protein (TGFBIp), an extracellular matrix protein, is the
second most abundant protein in the corneal stroma. In this review, we summarize the …

Purpose: The majority of anterior corneal dystrophies are caused by dominant mutations in
TGFBI (transforming growth factor β-induced) collectively known as the epithelial-stromal …

TGFBI-associated corneal dystrophies are inherited disorders caused by TGFBI gene
variants that promote deposition of mutant protein (TGFBIp) as insoluble aggregates in the …

This study evaluated whether lithium chloride (LiCl) prevents cytoplasmic accumulation of
mutant-transforming growth factor β-induced protein (Mut-TGFBI) in granular corneal …

The serine protease high-temperature requirement protein A1 (HtrA1) is associated with
protein-misfolding disorders such as Alzheimer's disease and transforming growth factor β …

PURPOSE: To investigate the long-term clinical outcomes and recurrence patterns of
phototherapeutic keratectomy (PTK) in patients with granular corneal dystrophy type 2 …

Scope The purpose of this study is to identify and visualize the spatial distribution of proteins
present in amyloid corneal deposits of TGFBI‐CD patients using Mass Spectrometry Imaging …

Purpose Granular corneal dystrophy type 2 (GCD2) is an autosomal dominant disorder and
is associated with the arginine to histidine substitution at codon 124 (p. R124H) of the TGFBI …

Purpose: To report the outcome of unilateral small incision lenticule extraction (SMILE) in a
patient with granular corneal dystrophy type 2 (GCD2). Methods: Slit-lamp photography and …

Corneal dystrophies are a group of genetically inherited disorders with mutations in the
TGFBI gene affecting the Bowman's membrane and the corneal stroma. The mutant TGFBIp …