Label-free SERS in biological and biomedical applications: recent progress, current challenges and opportunities

XS Zheng, IJ Jahn, K Weber, D Cialla-May… - Spectrochimica Acta Part …, 2018 - Elsevier
To achieve an insightful look within biomolecular processes on the cellular level, the
development of diseases as well as the reliable detection of metabolites and pathogens, a …

Application of SERS in the Detection of Fungi, Bacteria and Viruses

J Xia, W Li, M Sun, H Wang - Nanomaterials, 2022 - mdpi.com
In this review, we report the recent advances of SERS in fungi, bacteria, and viruses. Firstly,
we briefly introduce the advantage of SERS over fluorescence on virus identification and …

Surface enhanced Raman scattering artificial nose for high dimensionality fingerprinting

N Kim, MR Thomas, MS Bergholt, IJ Pence… - Nature …, 2020 - nature.com
Label-free surface-enhanced Raman spectroscopy (SERS) can interrogate systems by
directly fingerprinting their components' unique physicochemical properties. In complex …

Exploring the margins of SERS in practical domain: An emerging diagnostic modality for modern biomedical applications

MM Joseph, N Narayanan, JB Nair, V Karunakaran… - Biomaterials, 2018 - Elsevier
Excellent multiplexing capability, molecular specificity, high sensitivity and the potential of
resolving complex molecular level biological compositions augmented the diagnostic …

Characterization of a G-quadruplex from hepatitis B virus and its stabilization by binding TMPyP4, BRACO19 and PhenDC3

OR Molnár, A Végh, J Somkuti, L Smeller - Scientific Reports, 2021 - nature.com
Specific guanine rich nucleic acid sequences can form non-canonical structures, like the
four stranded G-quadruplex (GQ). We studied the GQ-forming sequence (named HepB) …

Metabolite profiling of human blood by surface-enhanced Raman spectroscopy for surgery assessment and tumor screening in breast cancer

D Lin, Y Wang, T Wang, Y Zhu, X Lin, Y Lin… - Analytical and …, 2020 - Springer
Mammography, a standard screening method for breast cancer, is effective for reducing the
rate of death; however, it suffers from frequent false positive alarm and radiation risk …

Structural features of DNA G-quadruplexes revealed by surface-enhanced Raman spectroscopy

Y Li, X Han, S Zhou, Y Yan, X Xiang… - The Journal of …, 2018 - ACS Publications
Surface-enhanced Raman spectroscopy (SERS) has been successfully used for the label-
free detection of single-stranded oligonucleotides. However, the detection of complex DNA …

Styryl dyes with N-Methylpiperazine and N-Phenylpiperazine Functionality: AT-DNA and G-quadruplex binding ligands and theranostic agents

I Zonjić, MR Stojković, I Crnolatac, AT Paić… - Bioorganic …, 2022 - Elsevier
New monomethine, unsymmetrical styryl dyes consisting of benzothiazole and N-
methylpiperazine or N-phenylpiperazine scaffolds were synthesized, and their binding …

Development of Mn2+-Specific Biosensor Using G-Quadruplex-Based DNA

M Mizunuma, M Suzuki, T Kobayashi, Y Hara… - International Journal of …, 2023 - mdpi.com
Metal ions are used in various situations in living organisms and as a part of functional
materials. Since the excessive intake of metal ions can cause health hazards and …

Revealing the effect of intramolecular interactions on DNA SERS detection: SERS capability for structural analysis

Y Bao, X Zhang, X Xiang, Y Zhang, B Zhao… - Physical Chemistry …, 2022 - pubs.rsc.org
Intramolecular interactions are key factors for constructing the secondary conformations of
biomolecules and they are also vital for biomolecular functions. Their effect on the surface …