Pseudomonas aeruginosa: An Audacious Pathogen with an Adaptable Arsenal of Virulence Factors

I Jurado-Martín, M Sainz-Mejías… - International journal of …, 2021 - mdpi.com
Pseudomonas aeruginosa is a dominant pathogen in people with cystic fibrosis (CF)
contributing to morbidity and mortality. Its tremendous ability to adapt greatly facilitates its …

Evaluation of antibiotic resistance mechanisms in gram-negative bacteria

A Gauba, KM Rahman - Antibiotics, 2023 - mdpi.com
Multidrug-resistant Gram-negative bacterial infections are exponentially increasing, posing
one of the most urgent global healthcare and economic threats. Due to the lack of new …

Antibiotic adjuvants: Synergistic tool to combat multi-drug resistant pathogens

V Kumar, N Yasmeen, A Pandey… - Frontiers in Cellular …, 2023 - frontiersin.org
The rise of multi-drug resistant (MDR) pathogens poses a significant challenge to the field of
infectious disease treatment. To overcome this problem, novel strategies are being explored …

Insights into the mechanisms and key factors influencing biofilm formation by Aeromonas hydrophila in the food industry: a comprehensive review and bibliometric …

MA Rahman, S Akter, M Ashrafudoulla… - Food Research …, 2024 - Elsevier
Biofilm formation by Aeromonas hydrophila in the food industry poses significant challenges
to food safety and quality. Therefore, this comprehensive review aimed to provide insights …

[HTML][HTML] Therapeutic approaches for combating Pseudomonas aeruginosa infections

V Jangra, N Sharma, AK Chhillar - Microbes and Infection, 2022 - Elsevier
Pseudomonas aeruginosa is an opportunistic pathogen responsible for acute hospital-
acquired infections. This review described various therapeutic approaches to treat infections …

Navigating fluoroquinolone resistance in Gram-negative bacteria: A comprehensive evaluation

L Kherroubi, J Bacon… - JAC-Antimicrobial …, 2024 - academic.oup.com
Since the introduction of quinolone and fluoroquinolone antibiotics to treat bacterial
infections in the 1960s, there has been a pronounced increase in the number of bacterial …

Photodynamic inactivation (PDI) as a promising alternative to current pharmaceuticals for the treatment of resistant microorganisms

B Pucelik, JM Dąbrowski - Advances in inorganic Chemistry, 2022 - Elsevier
Although the whole world is currently observing the global battle against COVID-19, it
should not be underestimated that in the next 30 years, approximately 10 million people per …

[HTML][HTML] The Many Lives of Auranofin: How an Old Anti-Rheumatic Agent May Become a Promising Antimicrobial Drug

F Coscione, S Zineddu, V Vitali, M Fondi, L Messori… - Antibiotics, 2024 - mdpi.com
Auranofin (AF) is a gold-based compound with a well-known pharmacological and
toxicological profile, currently used in the treatment of some severe forms of rheumatoid …

Zebrafish and water microbiome recovery after oxytetracycline exposure

AR Almeida, I Domingues, I Henriques - Environmental Pollution, 2021 - Elsevier
Oxytetracycline (OTC) is a broad-spectrum antibiotic widely used in aquaculture, resulting in
contamination of aquatic environments. In a previous study, we observed significant effects …

Design, synthesis, and proof-of-concept of triple-site inhibitors against aminoacyl-tRNA synthetases

Z Cai, B Chen, Y Yu, J Guo, Z Luo… - Journal of Medicinal …, 2022 - ACS Publications
Aminoacyl-tRNA synthetases (aaRSs) are promising drug targets due to their essential roles
in protein translation. Although current inhibitors primarily occupy one or two of the three …