Architectural RNA in chromatin organization

J Thakur, S Henikoff - Biochemical Society Transactions, 2020 - portlandpress.com
RNA plays a well-established architectural role in the formation of membraneless
interchromatin nuclear bodies. However, a less well-known role of RNA is in organizing …

The cellular mechanisms and consequences of centromere drive

LE Kursel, HS Malik - Current Opinion in Cell Biology, 2018 - Elsevier
Highlights•Cortical CDC42 signaling leads to asymmetric tyrosination of meiosis I spindle
microtubules.•Centromeric DNA expansion recruits more CenH3, increases centromere …

High temperature increases centromere-mediated genome elimination frequency and enhances haploid induction in Arabidopsis

U Ahmadli, M Kalidass, LC Khaitova, J Fuchs… - Plant …, 2023 - cell.com
Double haploid production is the most effective way to create true-breeding lines in a single
generation. In Arabidopsis, haploid induction via mutation of the centromere-specific histone …

Kinetochore assembly throughout the cell cycle

AP Navarro, IM Cheeseman - Seminars in cell & developmental biology, 2021 - Elsevier
The kinetochore plays an essential role in facilitating chromosome segregation during cell
division. This massive protein complex assembles onto the centromere of chromosomes and …

Keeping the centromere under control: a promising role for DNA methylation

A Scelfo, D Fachinetti - Cells, 2019 - mdpi.com
In order to maintain cell and organism homeostasis, the genetic material has to be faithfully
and equally inherited through cell divisions while preserving its integrity. Centromeres play …

The role of centromeric repeats and transcripts in kinetochore assembly and function

J Ramakrishnan Chandra, M Kalidass… - The Plant …, 2024 - Wiley Online Library
Centromeres are the chromosomal domains, where the kinetochore protein complex is
formed, mediating proper segregation of chromosomes during cell division. Although the …

[HTML][HTML] The epigenetic regulation of centromeres and telomeres in plants and animals

M Achrem, I Szućko, A Kalinka - Comparative Cytogenetics, 2020 - ncbi.nlm.nih.gov
The centromere is a chromosomal region where the kinetochore is formed, which is the
attachment point of spindle fibers. Thus, it is responsible for the correct chromosome …

Nanoscale Structure, Interactions, and Dynamics of Centromere Nucleosomes

S Filliaux, Z Sun, YL Lyubchenko - Biomacromolecules, 2024 - ACS Publications
Centromeres are specific segments of chromosomes comprising two types of nucleosomes:
canonical nucleosomes containing an octamer of H2A, H2B, H3, and H4 histones and …

[HTML][HTML] Construction of an mRNA-miRNA-lncRNA network prognostic for triple-negative breast cancer

Y Huang, X Wang, Y Zheng, W Chen, Y Zheng… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
The aim of this study was to establish a novel competing endogenous RNA (ceRNA)
network able to predict prognosis in patients with triple-negative breast cancer (TNBC) …

Dynamic interplay between human alpha-satellite DNA structure and centromere functions

E Di Tommaso, S Giunta - Seminars in Cell & Developmental Biology, 2024 - Elsevier
Maintenance of genome stability relies on functional centromeres for correct chromosome
segregation and faithful inheritance of the genetic information. The human centromere is the …