Oncologic Impact and Safety of Pre-Operative Radiotherapy in Localized Prostate and Bladder Cancer: A Comprehensive Review from the Cancerology Committee of …

P Sargos, S Supiot, G Créhange, G Fromont-Hankard… - Cancers, 2021 - mdpi.com
Simple Summary Radiotherapy may have an interesting role of reinforcing the loco-regional
control of cancer, in addition to surgery, when used as a preoperative treatment. This …

Radiotherapy before and after radical prostatectomy for high-risk and locally advanced prostate cancer

BA Perez, BF Koontz - Urologic Oncology: Seminars and Original …, 2015 - Elsevier
Objectives Men with localized high-risk prostate cancer carry significant risk of prostate
cancer–specific mortality. The best treatment approach to minimize this risk is unclear. In this …

Phase 1 trial of stereotactic body radiation therapy neoadjuvant to radical prostatectomy for patients with high-risk prostate cancer

NR Parikh, AU Kishan, N Kane, S Diaz-Perez… - International Journal of …, 2020 - Elsevier
Purpose This study aimed to evaluate the feasibility and safety of prostate stereotactic body
radiation therapy (SBRT) neoadjuvant to radical prostatectomy (RP) in a phase 1 trial. The …

A phase 1 pilot study of preoperative radiation therapy for prostate cancer: Long-term toxicity and oncologic outcomes

R Glicksman, N Sanmamed, J Thoms, AR Zlotta… - International Journal of …, 2019 - Elsevier
Purpose Neoadjuvant radiation therapy (RT) improves disease control in various cancers
and has become an established oncologic treatment strategy. During 2001 to 2004, we …

A phase I trial of Neoadjuvant stereotactic body radiotherapy prior to radical prostatectomy for locally advanced prostate cancer

L Hammer, R Jiang, J Hearn, J Lashbrook… - International Journal of …, 2023 - Elsevier
Purpose Men with locally advanced prostate cancer who undergo radical prostatectomy
(RP) often develop recurrence and require postoperative radiotherapy. We aimed to …

Neoadjuvant radiohormonal therapy for oligo-metastatic prostate cancer: safety and efficacy outcomes from an open-label, dose-escalation, single-center, phase I/II …

Y Chang, X Zhao, Y Xiao, S Yan, W Xu, Y Wang… - Frontiers of …, 2023 - Springer
To evaluate the safety and efficacy of neoadjuvant radiohormonal therapy for oligometastatic
prostate cancer (OMPC), we conducted a 3+ 3 dose escalation, prospective, phase I/II …

Classifying high-risk versus very high-risk prostate cancer: is it relevant to outcomes of conformal radiotherapy and androgen deprivation?

A Saad, J Goldstein, YR Lawrence, B Spieler… - Radiation …, 2017 - Springer
Objective To evaluate outcomes in prostate cancer patients classified as high-risk (HR) or
very high-risk (VHR) who were treated with conformal radiation therapy (CRT) and androgen …

Safety and Efficacy of Neoadjuvant Docetaxel and Radiotherapy in Localized High-Risk Prostate Cancer: Results From a Prospective Pilot Study

KC Ohaegbulam, CM Post, PE Farris… - American Journal of …, 2024 - journals.lww.com
Objectives: Approximately 15% of patients with localized prostate cancer are at high risk for
disease recurrence. Many clinical trials have evaluated the impact of neoadjuvant therapy …

[PDF][PDF] 高危前列腺癌新辅助治疗的研究进展

杨高阳, 姜婧琦, 王羽含, 王志平 - 临床泌尿外科杂志, 2023 - lcmwen.whuhzzs.com
高危前列腺癌(HRPCa) 是一种异质性疾病, 易出现隐匿性转移, 治疗后易早期复发,
局部治疗(根治手术或放疗) 后生化复发率高达55%~ 70%. 前列腺癌新辅助治疗是指患者在接受 …

Assessing the safety and feasibility of neoadjuvant hormone and radiation therapy followed by robot-assisted radical prostatectomy for treating locally advanced …

YT Xiao, X Zhao, Y Chang, X Lu, Y Wang, H Zhang… - BMJ open, 2020 - bmjopen.bmj.com
Introduction Patients with locally advanced prostate cancer are at high risk of recurrence
after definitive treatment. There are emerging data that radical prostatectomy can delay the …