The potential of metabolomics in biomedical applications

V Gonzalez-Covarrubias, E Martínez-Martínez… - Metabolites, 2022 - mdpi.com
The metabolome offers a dynamic, comprehensive, and precise picture of the phenotype.
Current high-throughput technologies have allowed the discovery of relevant metabolites …

Understanding the role of the gut microbiome and microbial metabolites in obesity and obesity-associated metabolic disorders: current evidence and perspectives

N Vallianou, T Stratigou, GS Christodoulatos… - Current obesity …, 2019 - Springer
Purpose In this review, we summarize current evidence on the gut microbiome and microbial
metabolites in relation to obesity and obesity-associated metabolic disorders. Special …

Probiotics, prebiotics, synbiotics, postbiotics, and obesity: current evidence, controversies, and perspectives

N Vallianou, T Stratigou, GS Christodoulatos… - Current obesity …, 2020 - Springer
Abstract Purpose of Review In this review, we summarize current evidence on gut
microbiome and obesity; we discuss the role of probiotics, prebiotics, synbiotics, and …

A systematic review of metabolomic studies of childhood obesity: State of the evidence for metabolic determinants and consequences

E Handakas, CH Lau, R Alfano, VL Chatzi… - Obesity …, 2022 - Wiley Online Library
Childhood obesity has become a global epidemic and carries significant long‐term
consequences to physical and mental health. Metabolomics, the global profiling of small …

Integrated omics analysis reveals the alteration of gut microbe–metabolites in obese adults

R Li, X Huang, X Liang, M Su, KP Lai… - Briefings in …, 2021 - academic.oup.com
Obesity, a risk to health, is a global problem in modern society. The prevalence of obesity
was approximately 13% among world's adult population. Recently, several reports …

[HTML][HTML] Phthalate exposure and childhood overweight and obesity: Urinary metabolomic evidence

B Xia, Q Zhu, Y Zhao, W Ge, Y Zhao, Q Song… - Environment …, 2018 - Elsevier
Objective Metabolomics may unravel global metabolic changes in response to
environmental exposures and identify important biological pathways involved in the …

Composition of gut microbiota in obese and normal‐weight Mexican school‐age children and its association with metabolic traits

BE López‐Contreras, S Morán‐Ramos… - Pediatric …, 2018 - Wiley Online Library
Background Childhood obesity is a serious public health problem in Mexico. Adult gut
microbiota composition has been linked to obesity, but few studies have addressed the role …

Oryzanol attenuates high fat and cholesterol diet-induced hyperlipidemia by regulating the gut microbiome and amino acid metabolism

S Yan, J Chen, L Zhu, T Guo, D Qin, Z Hu… - Journal of Agricultural …, 2022 - ACS Publications
Hyperlipidemia is intricately associated with the dysregulation of gut microbiota and host
metabolomes. This study explored the antihyperlipidemic function of oryzanol and …

Gut microbiota in obesity and metabolic abnormalities: a matter of composition or functionality?

S Moran-Ramos, BE López-Contreras… - Archives of medical …, 2017 - Elsevier
The obesity pandemic and the metabolic complications derived from it represent a major
public health challenge worldwide. Although obesity is a multifactorial disease, research …

Novel high‐docosahexaenoic‐acid tuna oil supplementation modulates gut microbiota and alleviates obesity in high‐fat diet mice

J Zhang, C Yi, J Han, T Ming, J Zhou… - Food Science & …, 2020 - Wiley Online Library
Studies have documented the benefits of fish oil in different diseases because of its high n‐3
polyunsaturated fatty acid content. However, these studies mostly used commercially …