New Insights on Molecular Autopsy in Sudden Death: A Systematic Review

L Tomassini, G Ricchezze, P Fedeli, M Lancia… - Diagnostics, 2024 - mdpi.com
Sudden unexpected deaths often remain unresolved despite forensic examination, posing
challenges for pathologists. Molecular autopsy, through genetic testing, can reveal hidden …

Post-mortem genetic analysis of sudden unexplained death in a young cohort: A whole-exome sequencing study

S Wang, Y Chen, J Du, Z Wang, Z Lin, G Hong… - International Journal of …, 2023 - Springer
Sudden unexplained death (SUD) constitutes a considerable portion of unexpected sudden
death in the young. Molecular autopsy has proved to be an efficient diagnostic tool in the …

Post-mortem genetic testing in sudden cardiac death and genetic screening of relatives at risk: Lessons learned from a Czech pilot multidisciplinary study

P Votýpka, A Krebsová… - International Journal of …, 2023 - Springer
Sudden cardiac death (SCD) might have an inherited cardiac condition background. Genetic
testing supports post-mortem diagnosis and screening of relatives at risk. Our aim is to …

Proteomic profiling of sudden cardiac death with acquired cardiac hypertrophy

Y Kakimoto, A Ueda, M Ito, M Tanaka, T Kubota… - International Journal of …, 2023 - Springer
Background Cardiac hypertrophy, which develops in middle-aged and older individuals as a
consequence of hypertension and obesity, is an established risk factor for sudden cardiac …

The power of hybridization capture-Illustrated using an expanded gene panel on 100 post mortem samples, focusing on sudden unexplained death

D Kling, E Adolfsson, H Gréen, A Gréen - Forensic Science International …, 2025 - Elsevier
Sudden unexpected death (SUD) is an unexpected event that in many cases are caused by
diseases with an underlying genetic background. Forensic molecular autopsy is an …

Molecular autopsy in Chinese sudden cardiac death in the young

SY Kwok, S Ho, FY Shih, PK Yeung… - American Journal of …, 2024 - Wiley Online Library
Inherited cardiovascular conditions are significant causes of sudden cardiac death in the
young (SCDY), making their investigation using molecular autopsy and prevention a public …

Genetic investigations of 100 inherited cardiac disease-related genes in deceased individuals with schizophrenia

SL Christiansen, JD Andersen, GE Themudo… - International Journal of …, 2021 - Springer
Cardiac diseases and sudden cardiac death (SCD) are more prevalent in individuals
diagnosed with schizophrenia compared to the general population, with especially coronary …

Use of potassium ion channel and spliceosome proteins as diagnostic biomarkers for sudden unexplained death in schizophrenia

M Zhang, S Wang, X Tang, X Ye, Y Chen, Z Liu… - Forensic Science …, 2022 - Elsevier
Sudden unexplained death in schizophrenia (SUD-SCZ) is not uncommon and its incidence
is approximately three times higher than that in the general population. However, diagnosis …

[HTML][HTML] Роль генетических исследований в профилактике жизнеугрожающих нарушений ритма и проводимости сердца у молодых

ЕН Логинова, ЕА Кирх, ГИ Нечаева… - Российский …, 2022 - cyberleninka.ru
По данным эпидемиологических исследований, в России отмечается тенденция к росту
внезапной сердечной смерти (ВСС), в т. ч. среди лиц молодого, трудоспособного …

Molecular autopsy and subsequent functional analysis reveal de novo DSG2 mutation as cause of sudden death

E Simons, A Labro, J Saenen, A Nijak… - European Journal of …, 2021 - Elsevier
Sudden cardiac death (SCD) is a common cause of death in young adults. In up to 80% of
cases a genetic cause is suspected. Next-generation sequencing of candidate genes can …