Calcium channels, synaptic plasticity, and neuropsychiatric disease

E Nanou, WA Catterall - Neuron, 2018 - cell.com
Voltage-gated calcium channels couple depolarization of the cell-surface membrane to entry
of calcium, which triggers secretion, contraction, neurotransmission, gene expression, and …

The mechanisms and functions of synaptic facilitation

SL Jackman, WG Regehr - Neuron, 2017 - cell.com
The ability of the brain to store and process information relies on changing the strength of
connections between neurons. Synaptic facilitation is a form of short-term plasticity that …

Voltage-gated calcium channels

WA Catterall - Cold Spring Harbor perspectives in …, 2011 - cshperspectives.cshlp.org
Voltage-gated calcium (Ca2+) channels are key transducers of membrane potential
changes into intracellular Ca2+ transients that initiate many physiological events. There are …

Short-term synaptic plasticity

RS Zucker, WG Regehr - Annual review of physiology, 2002 - annualreviews.org
▪ Abstract Synaptic transmission is a dynamic process. Postsynaptic responses wax and
wane as presynaptic activity evolves. This prominent characteristic of chemical synaptic …

The medial frontal cortex and the rapid processing of monetary gains and losses

WJ Gehring, AR Willoughby - Science, 2002 - science.org
We report the observation of neural processing that occurs within 265 milliseconds after
outcome stimuli that inform human participants about gains and losses in a gambling task. A …

Structure and Regulation of Voltage-Gated Ca2+ Channels

WA Catterall - Annual review of cell and developmental biology, 2000 - annualreviews.org
▪ Abstract Voltage-gated Ca2+ channels mediate Ca2+ entry into cells in response to
membrane depolarization. Electrophysiological studies reveal different Ca2+ currents …

Short-term presynaptic plasticity

WG Regehr - Cold Spring Harbor perspectives in biology, 2012 - cshperspectives.cshlp.org
Different types of synapses are specialized to interpret spike trains in their own way by virtue
of the complement of short-term synaptic plasticity mechanisms they possess. Numerous …

P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury

M Tsuda, Y Shigemoto-Mogami, S Koizumi… - Nature, 2003 - nature.com
Pain after nerve damage is an expression of pathological operation of the nervous system,,
one hallmark of which is tactile allodynia—pain hypersensitivity evoked by innocuous …

Multiple roles of calcium ions in the regulation of neurotransmitter release

E Neher, T Sakaba - Neuron, 2008 - cell.com
The intracellular calcium concentration ([Ca 2+]) has important roles in the triggering of
neurotransmitter release and the regulation of short-term plasticity (STP). Transmitter …

LTRPC7 is a Mg· ATP-regulated divalent cation channel required for cell viability

MJS Nadler, MC Hermosura, K Inabe, AL Perraud… - Nature, 2001 - nature.com
The molecular mechanisms that regulate basal or background entry of divalent cations into
mammalian cells are poorly understood. Here we describe the cloning and functional …