Solar radiation induces acute and chronic reactions in human and animal skin. Chronic
repeated exposures are the primary cause of benign and malignant skin tumors, including …

The skin being a protective barrier between external and internal (body) environments has
the sensory and adaptive capacity to maintain local and global body homeostasis in …

Redox-regulated processes are relevant to wound healing. A balance between bioavailable
nitric oxide (NO) concentration and a level of oxidative and nitroxidative stress in wounds …

Oxidative stress is involved in the pathogenesis of various degenerative diseases including
cancer. It is now recognized that low levels of oxidants can modify cell-signaling proteins …

There is increasing evidence for the generation of reactive oxygen species in skin upon
ultraviolet exposure, but little is known about their pathophysiologic relevance in human skin …

Endogenous chromophores in human skin serve as photosensitizers involved in skin
photocarcinogenesis and photoaging. Absorption of solar photons, particularly in the UVA …

Cancer chemoprevention is defined as the use of natural, synthetic, or biologic chemical
agents to reverse, suppress, or prevent carcinogenic progression to invasive cancer. The …

Melanoma and nonmelanoma skin cancers are among the most prevalent cancers in the
human population. Solar ultraviolet radiation is considered a major etiological factor but the …

Physical trauma represents one of the most primitive challenges that threatened survival.
Healing a problem wound requires a multi-faceted comprehensive approach. First and …

Rosacea is a common and chronic inflammatory skin disease that affects over 10 million
Americans. Although the phenotypes of rosacea are clinically heterogeneous, they are all …