[HTML][HTML] Macrophage-related therapeutic strategies: Regulation of phenotypic switching and construction of drug delivery systems

X Wang, Y Li, X Pu, G Liu, H Qin, W Wan, Y Wang… - Pharmacological …, 2024 - Elsevier
Macrophages, as highly phenotypic plastic immune cells, play diverse roles in different
pathological conditions. Changing and controlling the phenotypes of macrophages is …

[HTML][HTML] Engineering white blood cell membrane-camouflaged nanocarriers for inflammation-related therapeutics

W Song, P Jia, Y Ren, J Xue, B Zhou, X Xu, Y Shan… - Bioactive materials, 2023 - Elsevier
White blood cells (WBCs) play essential roles against inflammatory disorders, bacterial
infections, and cancers. Inspired by nature, WBC membrane-camouflaged nanocarriers …

siRNA delivery against myocardial ischemia reperfusion injury mediated by reversibly camouflaged biomimetic nanocomplexes

Y Zhou, Q Liang, X Wu, S Duan, C Ge, H Ye… - Advanced …, 2023 - Wiley Online Library
Abstract siRNA‐mediated management of myocardial ischemia reperfusion (IR) injury is
greatly hampered by the inefficient myocardial enrichment and cardiomyocyte transfection …

A multifunctional nanoparticle mitigating cytokine storm by scavenging multiple inflammatory mediators of sepsis

Z Li, Y Feng, S Zhang, T Li, H Li, D Wang, K Hao… - ACS …, 2023 - ACS Publications
Sepsis is a disease caused by infection, which is characterized by a dysregulated immune
response in the host and affects more than 30 million people worldwide each year …

Atmosphere-inspired multilayered nanoarmor with modulable protection and delivery of Interleukin-4 for inflammatory microenvironment modulation

X Ge, J Hu, Y Peng, Z Zeng, D He, X Li, Y Chen, G Luo… - Biomaterials, 2023 - Elsevier
Inflammatory bowel disease (IBD) has been closely associated with immune disorders and
excessive M1 macrophage activation, which can be reversed by the M2-polarizing effect of …

Capsulated Cellular Nanosponges for the Treatment of Experimental Inflammatory Bowel Disease

Y Duan, E Zhang, RH Fang, W Gao, L Zhang - ACS nano, 2023 - ACS Publications
Inflammatory bowel disease (IBD) is a chronic gastrointestinal tract disorder characterized
by uncontrolled inflammatory responses to the disrupted intestinal epithelial barrier and gut …

An optimally designed engineering exosome–reductive COF integrated nanoagent for synergistically enhanced diabetic fester wound healing

B Sun, F Wu, X Wang, Q Song, Z Ye… - Small, 2022 - Wiley Online Library
Oxidative stress and local overactive inflammation have been considered major obstacles in
diabetic wound treatment. Although antiphlogistic tactics have been reported widely, they …

Wielding the double-edged sword: Redox drug delivery systems for inflammatory bowel disease

Y Chen, M Shui, Q Yuan, CT Vong, Z Yang… - Journal of Controlled …, 2023 - Elsevier
The etiology of inflammatory bowel disease (IBD) is extremely complex and related to an
excessive immune response that results in the pathologically release of reactive oxygen …

Inflammation-responsive nanoagents for activatable photoacoustic molecular imaging and tandem therapies in rheumatoid arthritis

Y Zhang, X Kang, J Li, J Song, X Li, W Li, J Qi - ACS nano, 2024 - ACS Publications
Rheumatoid arthritis (RA) severely lowers the life quality by progressively destructing joint
functions and eventually causing permanent disability, representing a pressing public health …

An Immunomodulatory Biomimetic Single‐Atomic Nanozyme for Biofilm Wound Healing Management

J Zhang, M Lv, X Wang, F Wu, C Yao, J Shen, N Zhou… - Small, 2023 - Wiley Online Library
Nanozyme‐driven catalytic antibacterial therapy has become a promising modality for
bacterial biofilm infections. However, current catalytic therapy of biofilm wounds is severely …