The enzyme UDP-glucose: glycoprotein glucosyltransferase (UGGT) is the gatekeeper of
protein folding within the endoplasmic reticulum (ER). One-third of the human proteome …

Selenium-enriched egg white peptides (Se-EWP) were prepared by pre-heat treatment and
enzymatic hydrolysis in this study. In addition, their selenopeptide sequence identification …

Human SELENOF is an endoplasmic reticulum (ER) selenoprotein that contains the redox
active motif CXU (C is cysteine and U is selenocysteine), resembling the redox motif of thiol …

Selenium-enriched peptide (SP) is a new type of selenium supplement with unique
bioactivities; however, its instability jeopardizes its industrial applications. Hence, a system …

Selenoprotein F (SelF) is an endoplasmic reticulum-residing eukaryotic protein that contains
a selenocysteine (Sec) residue. It has been suggested to be involved in a number of …

Tyrosine sulfation is an important post-translational modification that enhances the inhibitory
activity of hirudin. Herein, we developed a facile synthetic strategy to afford the sulfated …

Herein, we developed a bifunctional reagent rac-2-Br-DMNPA 2 for the late-stage protection
of peptide cysteine. Through the identification of its t-Bu ester 1 as a more competent form …

Native chemical ligation (NCL) has been playing an increasingly important role in chemical
protein synthesis (CPS). More efficient ligation methods that circumvent the requirement of a …

C‐terminal hydrazides are an important class of synthetic peptides with an ever expanding
scope of applications, but their widespread application for chemical protein synthesis has …

Triabin, a lipocalin-like thrombin inhibitor from the saliva of the blood-sucking triatomine bug
Triatoma pallidipennis, exhibits effective inhibition comparable to hirudin despite binding …