Major depression disorder (MDD) is a debilitating mental illness with significant morbidity
and mortality. Despite the growing number of studies that have emerged, the precise …

Psychiatric disorders are characterized by sex differences in their prevalence,
symptomatology and treatment response. Animal models have been widely employed for …

Animal studies over the past two decades have led to extensive advances in our
understanding of pathogenesis of depressive and mood disorders. Among these, rodent …

Many stress‐related mental disorders, including depression and post‐traumatic stress
disorder occur more often in women than in men. While social and cultural factors certainly …

In clinical populations, sex differences in disease prevalence, symptoms and outcome have
been established. Despite this, female rats are frequently omitted from preclinical research; …

Clinical studies have shown that women are more susceptible to depression than men. Sex
differences in depression have been associated with social, cultural, as well as biological …

Women are more susceptible than men to certain stress-related psychiatric disorders, such
as depression. Preclinical studies aim to understand these sex differences by studying male …

Clinical and experimental evidence suggest that estrogens have a major impact on
cognition, presenting neurotrophic and neuroprotective actions in regions involved in such …

Behavioural pharmacology relies on animal models which are primarily validated using the
male laboratory rat. Many researchers solely employ male animals in studies; this is …

This study investigated sex‐specific effects of repeated stress and food restriction on food
intake, body weight, corticosterone plasma levels and expression of corticotropin‐releasing …