Spondyloarthritis with inflammatory bowel disease: the latest on biologic and targeted therapies

G Cozzi, L Scagnellato, M Lorenzin… - Nature Reviews …, 2023 - nature.com
Spondyloarthritis (SpA) encompasses a heterogeneous group of chronic inflammatory
diseases that can affect both axial and peripheral joints, tendons and entheses. Among the …

Inflammatory bowel disease: a comprehensive analysis of molecular bases, predictive biomarkers, diagnostic methods, and therapeutic options

E Diez-Martin, L Hernandez-Suarez… - International Journal of …, 2024 - mdpi.com
In inflammatory bowel diseases (IBDs), such as Crohn's disease (CD) and ulcerative colitis
(UC), the immune system relentlessly attacks intestinal cells, causing recurrent tissue …

Diagnosis and management of inflammatory bowel disease

L Li, R Cheng, Y Wu, H Lin, H Gan… - Journal of Evidence …, 2024 - Wiley Online Library
Inflammatory bowel disease (IBD) is a chronic and relapsing immune‐mediated disease of
the gastrointestinal tract with a gradually increasing global incidence and prevalence. A …

The role of genetic and epigenetic regulation in Intestinal Fibrosis in Inflammatory Bowel Disease: a descending process or a programmed consequence?

S Jarmakiewicz-Czaja, A Sokal, K Ferenc, E Motyka… - Genes, 2023 - mdpi.com
Inflammatory bowel diseases (IBDs) are a group of chronic diseases characterized by
recurring periods of exacerbation and remission. Fibrosis of the intestine is one of the most …

Novel biomarkers for inflammatory bowel disease and colorectal cancer: an interplay between metabolic dysregulation and excessive inflammation

M Salla, J Guo, H Joshi, M Gordon, H Dooky… - International Journal of …, 2023 - mdpi.com
Persistent inflammation can trigger altered epigenetic, inflammatory, and bioenergetic
states. Inflammatory bowel disease (IBD) is an idiopathic disease characterized by chronic …

Role of Serum Interleukin-6, Interleukin-1β and Interleukin-10 in Assessment of Disease Activity and Nutritional Status in Patients with Inflammatory Bowel Disease

M Godala, E Gaszyńska, K Walczak… - Journal of Clinical …, 2023 - mdpi.com
Inflammatory bowel diseases (IBD) are characterised by multifactorial and chronic
inflammation. Much attention has been paid to immune dysfunction in inflammatory bowel …

Emerging microfluidic gut-on-a-chip systems for drug development

X Wang, Y Zhu, Z Cheng, C Zhang, Y Liao, B Liu… - Acta Biomaterialia, 2024 - Elsevier
The gut is a vital organ that is central to the absorption and metabolic processing of orally
administered drugs. While there have been many models developed with the goal of …

[HTML][HTML] Enhanced transcription of human endogenous retroviruses and TRIM28 downregulation in patients with inflammatory bowel disease

PA Tovo, DG Ribaldone, I Galliano, GP Caviglia, M Dini… - Viruses, 2024 - mdpi.com
Inflammatory bowel disease (IBD) includes patients affected by Crohn's disease or
ulcerative colitis. IBD is thought to be a chronic immune-mediated disease, but its origin …

The earlier you find, the better you treat: red flags for early diagnosis of inflammatory bowel disease

L Cantoro, R Monterubbianesi, G Falasco, C Camastra… - Diagnostics, 2023 - mdpi.com
Delayed diagnosis is a challenge in the management of inflammatory bowel disease (IBD).
Several studies show a significant association between diagnostic delay and disease …

The role of mesenchymal stem cells in attenuating inflammatory bowel disease through ubiquitination

HX Liao, X Mao, L Wang, N Wang… - Frontiers in …, 2024 - frontiersin.org
Inflammatory bowel disease (IBD), a condition of the digestive tract and one of the
autoimmune diseases, is becoming a disease of significant global public health concern and …