This article summarizes the recent progress in the design and synthesis of hydrogels as
tissue-engineering scaffolds. Hydrogels are attractive scaffolding materials owing to their …

Bone defects represent a medical and socioeconomic challenge. Different types of
biomaterials are applied for reconstructive indications and receive rising interest. However …

Copper-containing bioactive glass nanoparticles (Cu-BG NPs) with designed compositions
and sizes were synthesized and incorporated into chitosan (CH)/silk fibroin …

A tissue-engineered implant is a biologic-biomaterial combination in which some
component of tissuehas been combined with a biomaterial to create a device for the …

Biomaterials developed for tissue engineering and wound healing applications need to
support robust cell adhesion, yet also need to be replaced by new tissue synthesized by …

One of the continued challenges in engineering clinically applicable tissues is the
establishment of vascularization upon implantation in vivo. Although the effectiveness of an …

Background Skin injury and the resultant defects are common clinical problems, and usually
lead to chronic skin ulcers and even life-threatening diseases. Copper, an essential trace …

Functional and perfusable vascular network formation is critical to ensure the long-term
survival and functionality of engineered tissues after their transplantation. Although several …

A key challenge in engineering functional tissues in vitro is the limited transport capacity of
oxygen and nutrients into the tissue. Inducing vascularization within engineered tissues is a …

The ability to create thick tissues is a major tissue engineering challenge, requiring the
development of a suitable vascular supply. Current trends are seeing the utilization of cells …