Therapeutic targeting of NF-κB in acute lung injury: a double-edged sword

MW Millar, F Fazal, A Rahman - Cells, 2022 - mdpi.com
Acute lung injury/acute respiratory distress syndrome (ALI/ARDS) is a devastating disease
that can be caused by a variety of conditions including pneumonia, sepsis, trauma, and most …

Paraquat poisonings: mechanisms of lung toxicity, clinical features, and treatment

RJ Dinis-Oliveira, JA Duarte… - Critical reviews in …, 2008 - Taylor & Francis
Paraquat dichloride (methyl viologen; PQ) is an effective and widely used herbicide that has
a proven safety record when appropriately applied to eliminate weeds. However, over the …

Intravenous high-dose vitamin C for the treatment of severe COVID-19: study protocol for a multicentre randomised controlled trial

F Liu, Y Zhu, J Zhang, Y Li, Z Peng - BMJ open, 2020 - bmjopen.bmj.com
Introduction The rapid worldwide spread of COVID-19 has caused a global health crisis. To
date, symptomatic supportive care has been the most common treatment. It has been …

[HTML][HTML] Targeting NOX4 alleviates sepsis-induced acute lung injury via attenuation of redox-sensitive activation of CaMKII/ERK1/2/MLCK and endothelial cell barrier …

J Jiang, K Huang, S Xu, JGN Garcia, C Wang, H Cai - Redox biology, 2020 - Elsevier
Increased pulmonary vascular permeability due to endothelial cell (EC) barrier dysfunction
is a major pathological feature of acute respiratory distress syndrome/acute lung injury …

[PDF][PDF] Albumin: biochemical properties and therapeutic potential

GJ Quinlan, GS Martin, TW Evans - Hepatology, 2005 - Wiley Online Library
Human serum albumin (HSA) is an abundant mul-tifunctional non-glycosylated, negatively
charged plasma protein, with ascribed ligand-binding and transport properties, antioxidant …

Generation and biological activities of oxidized phospholipids

VN Bochkov, OV Oskolkova, KG Birukov… - Antioxidants & redox …, 2010 - liebertpub.com
Glycerophospholipids represent a common class of lipids critically important for integrity of
cellular membranes. Oxidation of esterified unsaturated fatty acids dramatically changes …

Biomarkers in acute lung injury

D Mokra, P Kosutova - Respiratory physiology & neurobiology, 2015 - Elsevier
Acute respiratory distress syndrome (ARDS) and its milder form acute lung injury (ALI) may
result from various diseases and situations including sepsis, pneumonia, trauma, acute …

Rapid and sensitive detection of protein biomarker using a portable fluorescence biosensor based on quantum dots and a lateral flow test strip

Z Li, Y Wang, J Wang, Z Tang, JG Pounds… - Analytical …, 2010 - ACS Publications
A portable fluorescence biosensor with rapid and ultrasensitive response for protein
biomarker has been built up with quantum dots and a lateral flow test strip. The superior …

Proteins as biomarkers of oxidative/nitrosative stress in diseases: the contribution of redox proteomics

I Dalle‐Donne, A Scaloni, D Giustarini… - Mass spectrometry …, 2005 - Wiley Online Library
Abstract I. Introduction 00 II. Reactive Oxygen and Nitrogen Species 00 III. Biological
Markers of Oxidative/Nitrosative Stress 00 IV. Oxidative/Nitrosative Stress and Protein …

Inflammation and lung cancer: roles of reactive oxygen/nitrogen species

N Azad, Y Rojanasakul, V Vallyathan - Journal of Toxicology and …, 2008 - Taylor & Francis
The lung is a highly specialized organ that facilitates uptake of oxygen and release of
carbon dioxide. Due to its unique structure providing enormous surface area to outside …