Endothelial cells are important constituents of blood vessels that play critical roles in
cardiovascular homeostasis by regulating blood fluidity and fibrinolysis, vascular tone …

Signaling by H2S is proposed to occur via persulfidation, a posttranslational modification of
cysteine residues (RSH) to persulfides (RSSH). Persulfidation provides a framework for …

Introduction Folic acid is the most important dietary determinant of homocysteine (Hcy). Hcy
serves as a critical intermediate in methylation reactions. It is created from methionine and …

A metabolic imbalance between lipid synthesis and degradation can lead to hepatic lipid
accumulation, a characteristic of patients with non-alcoholic fatty liver disease (NAFLD) …

Abstract Hydrogen sulfide (H 2 S), in its gaseous form, plays an important role in tumor
carcinogenesis. This study investigated the effects of H 2 S on the cell biological functions of …

Hydrogen sulfide (H2S), emerging as an important gaseous signal, has attracted more and
more attention for its key role in chronic fatty liver diseases. However, lacking tools for H2S …

Conclusions FXR sulfhydration is a post‐translational modification affected by hepatic
endogenous CSE/H 2 S that may promote FXR activity and attenuate NAFLD. Hepatic CSE …

Objective Accumulation of free fatty acids (FFAs) in hepatocytes induces lipotoxicity, leading
to non-alcoholic fatty liver disease (NAFLD). This study aimed to investigate the underlying …

Autophagy plays an important role in liver triglyceride (TG) metabolism. Inhibition of
autophagy could reduce the clearance of TG in the liver. Hydrogen sulfide (H2S) is a potent …

Glioblastoma (GBM) remains among the deadliest of human malignancies, and the
emergence of the cancer stem cell (CSC) phenotype represents a major challenge to …