Natural bone constitutes a complex and organized structure of organic and inorganic
components with limited ability to regenerate and restore injured tissues, especially in large …

Bone resorption can negatively influence the osseointegration of dental implants. Barrier
membranes for guided bone regeneration (GBR) are used to exclude nonosteogenic tissues …

Bone tissue engineering is becoming an ideal strategy to replace autologous bone grafts for
surgical bone repair, but the multihierarchical complexity of natural bone is still difficult to …

Polypeptides with short chains of amino acid monomers have been widely applied in the
clinic because of their various biological functions. However, the easily‐inactivated …

Bone endoprosthesis in patients with systemic chronic inflammation frequently leads to poor
osseointegration after implantation mainly due to the increase in pro-inflammatory cytokines …

As orthopedic and dental implants, polyetheretherketone (PEEK) is expected to be a
common substitute material of titanium (Ti) and its alloys due to its good biocompatibility …

The overall aim of the current study is to develop a dual-functional PEEK implant to
simultaneously fight off bacterial contamination and promote osseointegration by sustained …

Bone formation or regeneration requires the recruitment, proliferation, and osteogenic
differentiation of stem/stromal progenitor cells. A potent stimulus driving this process is …

The bacterial infection, especially for methicillin-resistant Staphylococcus aureus (MRSA),
and the associated severe inflammatory response could extremely limit the crosstalk of …

Studies have demonstrated that scaffolds, a component of bone tissue engineering, play an
indispensable role in bone repair. However, these scaffolds involving ex-vivo cultivated cells …