Neuroplastic changes following brain ischemia and their contribution to stroke recovery: novel approaches in neurorehabilitation

C Alia, C Spalletti, S Lai, A Panarese… - Frontiers in cellular …, 2017 - frontiersin.org
Ischemic damage to the brain triggers substantial reorganization of spared areas and
pathways, which is associated with limited, spontaneous restoration of function. A better …

[HTML][HTML] MRI markers of functional connectivity and tissue microstructure in stroke-related motor rehabilitation: A systematic review

E Tavazzi, N Bergsland, A Pirastru, M Cazzoli… - NeuroImage: Clinical, 2022 - Elsevier
Background Stroke-related disability is a major problem at individual and socio-economic
levels. Neuromotor rehabilitation has a key role for its dual action on affected body segment …

Reducing GABAA-mediated inhibition improves forelimb motor function after focal cortical stroke in mice

C Alia, C Spalletti, S Lai, A Panarese, S Micera… - Scientific Reports, 2016 - nature.com
A deeper understanding of post-stroke plasticity is critical to devise more effective
pharmacological and rehabilitative treatments. The GABAergic system is one of the key …

Combining robotic training and inactivation of the healthy hemisphere restores pre-stroke motor patterns in mice

C Spalletti, C Alia, S Lai, A Panarese, S Conti, S Micera… - Elife, 2017 - elifesciences.org
Focal cortical stroke often leads to persistent motor deficits, prompting the need for more
effective interventions. The efficacy of rehabilitation can be increased by 'plasticity …

Transcranial magnetic stimulation therapy for central post-stroke pain: systematic review and meta-analysis

F Gurdiel-Álvarez, V Navarro-López… - Frontiers in …, 2024 - frontiersin.org
Introduction Although rare, central post-stroke pain remains one of the most refractory forms
of neuropathic pain. It has been reported that repetitive transcranial magnetic stimulation …

Lesion size-and location-dependent recruitment of contralesional thalamus and motor cortex facilitates recovery after stroke in mice

M Aswendt, N Pallast, F Wieters, M Baues… - Translational stroke …, 2021 - Springer
Brain lesions caused by cerebral ischemia or hemorrhage lead to a local breakdown of
energy homeostasis followed by irreversible cell death and long-term impairment …

Fast-spiking interneurons of the premotor cortex contribute to initiation and execution of spontaneous actions

N Giordano, C Alia, L Fruzzetti, M Pasquini… - Journal of …, 2023 - Soc Neuroscience
Planning and execution of voluntary movement depend on the contribution of distinct
classes of neurons in primary motor and premotor areas. However, timing and pattern of …

A robotic system for adaptive training and function assessment of forelimb retraction in mice

M Pasquini, S Lai, C Spalletti… - … on Neural Systems …, 2018 - ieeexplore.ieee.org
Rodent models are decisive for translational research in healthy and pathological conditions
of motor function thanks to specific similarities with humans. Here, we present an upgraded …

Low-intensity contralesional electrical theta burst stimulation modulates ipsilesional excitability and enhances stroke recovery

LJ Boddington, JP Gray, JM Schulz… - Experimental neurology, 2020 - Elsevier
Targeting interhemispheric inhibition using brain stimulation has shown potential for
enhancing stroke recovery. Following stroke, increased inhibition originating from the …

Network reorganization for neurophysiological and behavioral recovery following stroke

Y Qi, Y Xu, H Wang, Q Wang, M Li… - … System Agents in …, 2024 - benthamdirect.com
Stroke continues to be the main cause of motor disability worldwide. While rehabilitation has
been promised to improve recovery after stroke, efficacy in clinical trials has been mixed. We …